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Hepatitis B virus polymerase

 
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Viral reverse transcriptases.
Reverse transcriptases (RTs) play a major role in the replication of Retroviridae, Metaviridae, Pseudoviridae, Hepadnaviridae and… Expand
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2015
2015
Structure of the HIV-1 reverse transcriptase Q151M mutant: insights into the inhibitor resistance of HIV-1 reverse transcriptase and the structure of the nucleotide-binding pocket of Hepatitis B…
The structure of the HIV-1 reverse transcriptase Q151M mutant was determined at a resolution of 2.6 Å in space group P321. 
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2015
2015
Molecular Dynamics Simulation Approach to Understand Lamivudine Resistance in Hepatitis B Virus Polymerase
Hepatitis B virus (HBV) is a global threat that killed many human lives. HBV DNA polymerase (HDP) is the key target for antiviral… Expand
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2011
2011
[Identification of ubiquitously expressed transcript as the potential interactor of hepatitis B virus polymerase].
OBJECTIVE To investigate the function of hepatitis B virus polymerase (HBV Pol) in the viral life cycle by screening the proteins… Expand
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Highly Cited
2003
Highly Cited
2003
Antisense Oligodeoxynucleotides Targeted against Molecular Chaperonin Hsp60 Block Human Hepatitis B Virus Replication*
The major role of hepatitis B virus polymerase (HBV pol) is polymerization of nucleotides, but it also participates in protein… Expand
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2003
2003
[Quasispecies and mutation of hepatitis B virus polymerase gene in lamivudine- treated patients].
OBJECTIVE To study the quasispecies and mutation features of hepatitis B virus polymerase (HBV P) gene in chronic hepatitis B… Expand
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2003
2003
[Detection and analysis of the new kind of G743C and G743A point mutation of HBV P gene in hepatitis B virus infected patients resistant to lamivudine].
OBJECTIVE To explore the point mutation in hepatitis B virus polymerase (HBV P) gene in HBV-infected patients resistant to… Expand
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Highly Cited
2001
Highly Cited
2001
Human Hepatitis B Virus Polymerase Interacts with the Molecular Chaperonin Hsp60
ABSTRACT Previous studies showed that hepatitis B virus polymerase (HBV Pol) interacts with host factors such as the Hsp90… Expand
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Highly Cited
1997
Highly Cited
1997
Comparison of cytotoxic T lymphocyte responses induced by peptide or DNA immunization: Implications on immunogenicity and immunodominance
To study the mechanisms that influence the immunogenicity and immunodominance of potential cytotoxic T lymphocyte (CTL) epitopes… Expand
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Highly Cited
1985
Highly Cited
1985
Amino acid homology between the encephalitogenic site of myelin basic protein and virus: mechanism for autoimmunity.
Amino acid sequence homology was found between viral and host encephalitogenic protein. Immune responses were then generated in… Expand
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