Hemophilia A

Known as: Classic Hemophilia, Hemophilia As, Haemophilia 
An inherited deficiency of coagulation factor VIII characterized by the tendency to spontaneous or exaggerated post-traumatic hemorrhage. Inherited… (More)

Topic mentions per year

Topic mentions per year

1936-2017
020040019362016

Papers overview

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Highly Cited
2013
Highly Cited
2013
Hemophilia is a rare disorder that is complex to diagnose and to manage. These evidence-based guidelines offer practical… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Hemophilia B, an X-linked disorder, is ideally suited for gene therapy. We investigated the use of a new gene therapy… (More)
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Highly Cited
2009
Highly Cited
2009
Hemophilia A is caused by mutations within the Factor VIII (FVIII) gene that lead to depleted protein production and inefficient… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Effective ways to prevent arthropathy in severe hemophilia are unknown. METHODS We randomly assigned young boys with… (More)
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Highly Cited
2007
Highly Cited
2007
Since the 1970s, mortality in the hemophilia population has been dominated by human immunodeficiency virus (HIV) and few reports… (More)
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Highly Cited
2007
Highly Cited
2007
Acquired hemophilia A is a severe bleeding disorder caused by an autoantibody to factor VIII. Previous reports have focused on… (More)
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Highly Cited
2003
Highly Cited
2003
Hemophilia B is an X-linked coagulopathy caused by absence of functional coagulation factor IX (F.IX). Previously, we established… (More)
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Highly Cited
1999
Highly Cited
1999
Hemophilia B is a severe X-linked bleeding diathesis caused by the absence of functional blood coagulation factor IX, and is an… (More)
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Highly Cited
1997
Highly Cited
1997
The critical role of chemokine receptors (CCR5 and CXCR4) in human immunodeficiency virus-type 1 (HIV-1) infection and… (More)
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Highly Cited
1996
Highly Cited
1996
The chemokine receptor 5 (CKR5) protein serves as a secondary receptor on CD4(+) T lymphocytes for certain strains of human… (More)
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