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Hematopoietic Stem Cell Mobilization

Known as: Mobilization, Stem Cell, Stem Cell Mobilization, stem cell mobilisation 
The release of stem cells from the bone marrow into the peripheral blood circulation for the purpose of leukapheresis, prior to stem cell… Expand
National Institutes of Health

Related topics

Related topics

4 relations
Apheresis (procedure)Hemopoietic stem cell transplantnursing therapystandards characteristics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
The bone marrow stem cell niche grows up: mesenchymal stem cells and macrophages move in
Ehninger and Trumpp discuss the role of monocytes/macrophages and other niche cells in the regulation of HSC mobilization and… Expand
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Highly Cited
2011
Highly Cited
2011
Diabetes impairs hematopoietic stem cell mobilization by altering niche function.
Success with transplantation of autologous hematopoietic stem and progenitor cells (HSPCs) in patients depends on adequate… Expand
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Highly Cited
2008
Highly Cited
2008
IGF-1-overexpressing mesenchymal stem cells accelerate bone marrow stem cell mobilization via paracrine activation of SDF-1alpha/CXCR4 signaling to promote myocardial repair.
We hypothesized that mesenchymal stem cells (MSCs) overexpressing insulin-like growth factor (IGF)-1 showed improved survival and… Expand
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Highly Cited
2008
Highly Cited
2008
Impact of mobilization and remobilization strategies on achieving sufficient stem cell yields for autologous transplantation.
The purpose of this article was to examine historic institutional autologous stem cell mobilization practices and evaluate… Expand
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Highly Cited
2006
Highly Cited
2006
Stem cell mobilization by granulocyte colony-stimulating factor in patients with acute myocardial infarction: a randomized controlled trial.
CONTEXT Experimental studies and early phase clinical trials suggest that transplantation of blood-derived or bone marrow-derived… Expand
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Review
2005
Review
2005
The bone marrow vascular niche: home of HSC differentiation and mobilization.
The bone marrow vascular niche consists of a network of thin-walled and fenestrated sinusoidal vessels whose integrity is… Expand
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Highly Cited
2003
Highly Cited
2003
Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells
Endothelial nitric oxide synthase (eNOS) is essential for neovascularization. Here we show that the impaired neovascularization… Expand
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Highly Cited
2003
Highly Cited
2003
Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide.
Hematopoietic progenitor cells (HPCs) normally reside in the bone marrow (BM) but can be mobilized into the peripheral blood (PB… Expand
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Highly Cited
2002
Highly Cited
2002
G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4
Granulocyte colony-stimulating factor (G-CSF)–induced hematopoietic stem cell mobilization is widely used for clinical… Expand
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Highly Cited
2000
Highly Cited
2000
Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells.
The ligand for the receptor tyrosine kinase fms-like tyrosine kinase 3 (flt3), also referred to as fetal liver kinase-2 (flk-2… Expand
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