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HSR 609

Known as: HSR-609 
National Institutes of Health

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2 relations

Broader (2)

BenzoxepinsPyridines

Papers overview

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2000
2000
Effect of a Novel Anti-Allergic Agent, HSR-609, on Antigen-Induced Airway Hyperresponsiveness in Mice
The effects of a newly synthesized anti-allergic agent, HSR-609, on allergic airway hyperresponsiveness and airway inflammation… 
2000
2000
Effects of an Amphoteric Antiallergic Agent, HSR-609, on Antigen-Induced Late Phase Nasal Eosinophilia in Brown Norway Rats
The effect of a newly synthesized compound, HSR-609, on rat experimental rhinitis was investigated. In the first part of the… 
1998
1998
Central nervous system effects of the novel antiallergic agent HSR-609 and typical antiallergic agents using behavioral and electroencephalographic analyses in dogs.
We studied the central nervous system (CNS) effects of 3-[4-(8-fluoro-5, 11-dihydrobenz[b] oxepino[4, 3-b]pyridin-11-ylidene… 
1998
1998
Scratching behavior in mice associated with IgE-mediated allergic cutaneous reaction and its pharmacological characterization
ABSTRACT Scratching behavior observed after epicutaneous challenge with the antigen 2,4-dinitrofluorobenzene (DNFB) in the ear of… 
1998
1998
HSR-609 : ANTIALLERGIC AGENT
1997
1997
Studies on the novel antiallergic agent HSR-609: its penetration into the central nervous system in mice and guinea pigs and its selectivity for the histamine H1-receptor.
We studied the pharmacological characteristics of HSR-609 (3-[4-(8-fluoro-5,11-dihydrobenz[b]oxepino[4,3-b]pyridin-11- ylidene… 
1997
1997
Pharmacological studies on the novel antiallergic agent HSR-609: its effects on behavior in mice and electroencephalograms in rabbits.
We studied the central nervous system (CNS) effects of HSR-609 (3-[4-(8-fluoro-5,11-dihydrobenz[b]oxepino[4,3-b]pyridin-11… 
1996
1996
Sensitive analytical method for the novel H1-receptor antagonist HSR-609 in human plasma and urine by high-performance liquid chromatography with pre-column fluorescent derivatization.
1995
1995
Amphoteric drugs. 3. Synthesis and antiallergic activity of 3-[(5,11-dihydro[1]benzoxepino[4,3-b]pyridin-11- ylidene)piperidino]propionic acid derivatives and related compounds.
An important approach to the design of antiallergic agents with reduced penetration into the central nervous system (CNS) is… 
1995
1995
Pharmacological studies of HSR-609, a novel amphoteric antiallergic agent (1) : Effects on various allergic models
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