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Investigations into the therapeutic properties of various combinations of the bispyridinium salts HS-3 and HS-6 and the… Expand Inhibition of bacterial metabolism by the lactoperoxidase (LP)-hydrogen peroxide (H2O2)-thiocyanate system was studied with… Expand Oxygen (O2) uptake and release of O2 metabolites to the extracellular medium were studied with representatives of serotypes a… Expand Atropinized rats intoxicated with ethyl-S-2-diisopropyl aminoethyl methyl phosphonothioate (VX), 15 mg/kg iv, were divided into… Expand Abstract Rabbits intoxicated with soman were treated with various doses of HS-6 at 3 min following administration of soman to… Expand Monkeys were exposed to varying doses of soman and given therapy. Therapy consisted of pyridostigmine, clonazepam, atropine and… Expand Abstract Bovine erythrocyte acetylcholinesterase inhibited by 1,2,2'-trimethylpropyl methylphosphonofluoridate (soman) is… Expand The effect of HS-6 [1-(2-hydroxyiminomethylpyridinium)-1-(3-carboxamidopyridinium)-dimethyl ether] on neuromuscular (NM… Expand The bisquaternary mono-oximes HS-6 and HI-6 may both be considered as potential therapeutic agents for soman intoxication. It has… Expand Atropinised anaesthetised rats were injected i.v. with 4, 6 or 8 X LD50 of the organophosphorous anticholinesterase soman… Expand