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HS 6

Known as: 1-(((3-(aminocarbonyl)pyridinio)methoxy)methyl)-2-((hydroxyimino)methyl)pyridinium dichloride, HS-6 
National Institutes of Health

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1 relation

Broader (1)

Pralidoxime Compounds

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1992
1992
Studies of the amplification of carbaryl toxicity by various oximes.
1983
1983
Reactivation of VX-inhibited cholinesterase by 2-PAM and HS-6 in rats.
Atropinized rats intoxicated with ethyl-S-2-diisopropyl aminoethyl methyl phosphonothioate (VX), 15 mg/kg iv, were divided into… 
1983
1983
Therapy of organophosphate poisoning: the marmoset as a model for man
1 The ability of various bis‐pyridinium oximes to restore organophosphate‐inhibited neuromuscular transmission in vitro was… 
Highly Cited
1980
Highly Cited
1980
Reactivation of acetylcholinesterase inhibited by 1,2,2'-trimethylpropyl methylphosphonofluoridate (soman) with HI-6 and related oximes.
1979
1979
The effects of atropine-oxime therapy on cholinesterase activity and survival of animals intoxicated with p-nitrophenyl di-n-butylphosphinate.
1979
1979
Pharmacological actions of HS-6, an oxime, on the neuromuscular junction.
Highly Cited
1978
Highly Cited
1978
A comparison of the oximes HS-6 and HI-6 in the therapy of soman intoxication in rodents.
1978
1978
The ganglionic blocking properties of the cholinesterase reactivator, HS-6.
Following intravenous administration of the cholinesterase reactivator HS-6 (30 mg/kg), blood pressure fell (up to 50 mmHg) and… 
1976
1976
Therapeutic effects of HS-3, HS-6, benactyzine, and atropine in soman poisoning of dogs
Investigations into the therapeutic properties of various combinations of the bispyridinium salts HS-3 and HS-6 and the… 
1976
1976
The dependence of the blood level of the oxime HS-6 on the severity of organophosphate poisoning.
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