Skip to search formSkip to main contentSkip to account menu

HRH4 gene

Known as: HRH4, GPCR105, AXOR35 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
The Role of Histamine and Histamine Receptors in Mast Cell-Mediated Allergy and Inflammation: The Hunt for New Therapeutic Targets
Histamine and its receptors (H1R–H4R) play a crucial and significant role in the development of various allergic diseases. Mast… 
Review
2014
Review
2014
Modulation of behavior by the histaminergic system: Lessons from HDC-, H3R- and H4R-deficient mice
Highly Cited
2013
Highly Cited
2013
Histamine induces proliferation in keratinocytes from patients with atopic dermatitis through the histamine 4 receptor.
2013
2013
Antitumor activity of histamine and clozapine in a mouse experimental model of human melanoma.
Highly Cited
2012
Highly Cited
2012
Histamine H4 Receptor Optimizes T Regulatory Cell Frequency and Facilitates Anti-Inflammatory Responses within the Central Nervous System
Histamine is a biogenic amine that mediates multiple physiological processes, including immunomodulatory effects in allergic and… 
2012
2012
Asthma Endophenotypes and Polymorphisms in the Histamine Receptor HRH4 Gene
Background: Histamine as an inflammatory mediator plays an important role in chronic allergic and asthmatic conditions. However… 
Highly Cited
2011
Highly Cited
2011
Probiotic Lactobacillus rhamnosus downregulates FCER1 and HRH4 expression in human mast cells.
AIM To investigate the effects of four probiotic bacteria and their combination on human mast cell gene expression using… 
2011
2011
Expression and functional properties of canine, rat, and murine histamine H4 receptors in Sf9 insect cells
The histamine H4 receptor (H4R) is expressed on cells of the immune system including eosinophils, dendritic cells, and T cells… 
2011
2011
Attenuated expression of HRH4 in colorectal carcinomas: a potential influence on tumor growth and progression
BackgroundEarlier studies have reported the production of histamine in colorectal cancers (CRCs). The effect of histamine is… 
Highly Cited
2007
Highly Cited
2007
Histamine 4 Receptor Activation Induces Recruitment of FoxP3+ T Cells and Inhibits Allergic Asthma in a Murine Model1
Histamine has an important role in regulation of immune response which is mediated by differential expression of four distinct… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)