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HOXB8 gene

Known as: HOMEOBOX B8, HOX2D, Hox-2.4, MOUSE, HOMOLOG OF 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
HOXB8 promotes tumor metastasis and the epithelial–mesenchymal transition via ZEB2 targets in gastric cancer
PurposeThe homeobox B8 (HOXB8) functions as a sequence-specific transcription factor that is involved in development. Increased… Expand
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2013
2013
Hoxb8 regulates expression of microRNAs to control cell death and differentiation
Hoxb8 overexpression immortalises haematopoietic progenitor cells in a growth-factor-dependant manner and co-operates with… Expand
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2013
2013
In vitro differentiation of near‐unlimited numbers of functional mouse basophils using conditional Hoxb8
Basophils constitute a rare leukocyte population known for their effector functions in inflammation and allergy, as well as more… Expand
Highly Cited
2008
Highly Cited
2008
Loss of Hoxb8 alters spinal dorsal laminae and sensory responses in mice
Although Hox gene expression has been linked to motoneuron identity, a role of these genes in development of the spinal sensory… Expand
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2006
2006
Distinct roles of Polycomb group gene products in transcriptionally repressed and active domains of Hoxb8
To address the molecular mechanisms underlying Polycomb group (PcG)-mediated repression of Hox gene expression, we have focused… Expand
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2006
2006
Medaka unextended-fin mutants suggest a role for Hoxb8a in cell migration and osteoblast differentiation during appendage formation.
Hoxb8 has been suggestively implicated in the formation of the zone of polarizing activity (ZPA) in the limb bud. However, as… Expand
Highly Cited
2004
Highly Cited
2004
MicroRNA-Directed Cleavage of HOXB8 mRNA
MicroRNAs (miRNAs) are endogenous ∼22-nucleotide RNAs, some of which are known to play important regulatory roles in animals by… Expand
Highly Cited
2002
Highly Cited
2002
Hoxb8 Is Required for Normal Grooming Behavior in Mice
Repertoires of grooming behaviors critical to survival are exhibited by most animal species, including humans. Genes that… Expand
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Highly Cited
2001
Highly Cited
2001
HoxB8 requires its Pbx-interaction motif to block differentiation of primary myeloid progenitors and of most cell line models of myeloid differentiation
HoxB8 was the first homeobox gene identified as a cause of leukemia. In murine WEHI3B acute myeloid leukemia (AML) cells… Expand
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Highly Cited
1999
Highly Cited
1999
Targeted inactivation of Hoxb8 affects survival of a spinal ganglion and causes aberrant limb reflexes
Hoxb8 mutant mice were generated by inserting the lacZ coding sequence in frame with the first exon of Hoxb8. These mice express… Expand
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