HOXB8 gene

Known as: HOMEOBOX B8, HOX2D, Hox-2.4, MOUSE, HOMOLOG OF 
 
National Institutes of Health

Papers overview

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2014
2014
FMRP regulates miR196a-mediated repression of HOXB8 via interaction with the AGO2 MID domain.
Fragile X syndrome (FXS) is caused by the loss of expression of fragile X mental retardation protein (FMRP), a selective RNA… Expand
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2013
2013
Hoxb8 regulates expression of microRNAs to control cell death and differentiation
Hoxb8 overexpression immortalises haematopoietic progenitor cells in a growth-factor-dependant manner and co-operates with… Expand
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2013
2013
In vitro differentiation of near-unlimited numbers of functional mouse basophils using conditional Hoxb8.
BACKGROUND Basophils constitute a rare leukocyte population known for their effector functions in inflammation and allergy, as… Expand
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2012
2012
HoxB8 in noradrenergic specification and differentiation of the autonomic nervous system.
Different prespecification of mesencephalic and trunk neural crest cells determines their response to environmental… Expand
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2008
2008
Loss of Hoxb8 alters spinal dorsal laminae and sensory responses in mice.
Although Hox gene expression has been linked to motoneuron identity, a role of these genes in development of the spinal sensory… Expand
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2006
2006
Distinct roles of Polycomb group gene products in transcriptionally repressed and active domains of Hoxb8.
To address the molecular mechanisms underlying Polycomb group (PcG)-mediated repression of Hox gene expression, we have focused… Expand
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Highly Cited
2004
Highly Cited
2004
MicroRNA-directed cleavage of HOXB8 mRNA.
MicroRNAs (miRNAs) are endogenous approximately 22-nucleotide RNAs, some of which are known to play important regulatory roles in… Expand
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Highly Cited
2002
Highly Cited
2002
Hoxb8 Is Required for Normal Grooming Behavior in Mice
Repertoires of grooming behaviors critical to survival are exhibited by most animal species, including humans. Genes that… Expand
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2001
2001
HoxB8 requires its Pbx-interaction motif to block differentiation of primary myeloid progenitors and of most cell line models of myeloid differentiation
HoxB8 was the first homeobox gene identified as a cause of leukemia. In murine WEHI3B acute myeloid leukemia (AML) cells… Expand
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1999
1999
Targeted inactivation of Hoxb8 affects survival of a spinal ganglion and causes aberrant limb reflexes
Hoxb8 mutant mice were generated by inserting the lacZ coding sequence in frame with the first exon of Hoxb8. These mice express… Expand
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