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HMGA2 Protein

Known as: HMGA2 Protein [Chemical/Ingredient], HMGI-C Protein, HMG I-C Protein 
High mobility group protein HMGI-C (109 aa, ~12 kDa) is encoded by the human HMGA2 gene. This protein is involved in the regulation of both mitosis… 
National Institutes of Health

Related topics

Related topics

28 relations
AT-Hook MotifsAdipogenesisCell Differentiation processDNA Topology Regulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
miR-302a-5p/367-3p-HMGA2 axis regulates malignant processes during endometrial cancer development
Metastasis is one of the main reasons for treatment failure in endometrial cancer. Notably, high mobility group AT-hook 2 (HMGA2… 
Review
2013
Review
2013
Molecular biomarkers as potential targets for therapeutic strategies in human testicular germ cell tumors: An overview
Testicular germ cell tumors (TGCTs), the most common malignancy in males between 15 and 34 years of age and the most frequent… 
2013
2013
Identification of CUX1 as the recurrent chromosomal band 7q22 target gene in human uterine leiomyoma
Uterine leiomyomas are benign solid tumors of mesenchymal origin which occur with an estimated incidence of up to 77% of all… 
Highly Cited
2012
Highly Cited
2012
Downregulation of HMGA2 by the pan-deacetylase inhibitor panobinostat is dependent on hsa-let-7b expression in liver cancer cell lines.
2011
2011
HMGA2 and p14Arf: major roles in cellular senescence of fibroids and therapeutic implications.
AIM To address the influence of genes involved in stem cell self-renewal and senescence on the growth of leiomyoma cells in vitro… 
2010
2010
HMGA2 and the p19Arf‐TP53‐CDKN1A axis: A delicate balance in the growth of uterine leiomyomas
Pathogenetically, uterine leiomyomas (ULs) can be interpreted as the result of a monoclonal abnormal proliferation of myometrial… 
Highly Cited
1999
Highly Cited
1999
A high frequency of tumors with rearrangements of genes of the HMGI(Y) family in a series of 191 pulmonary chondroid hamartomas
Pulmonary chondroid hamartomas (PCHs) are benign mesenchymal tumors that often are characterized by specific chromosomal… 
1998
1998
The t(3;12)(q27;q14‐q15) with underlying HMGIC‐LPP fusion is not determining an adipocytic phenotype
The HMGIC gene, located in chromosome band 12q15, is rearranged in many different benign human tumors, often resulting in its… 
1998
1998
Amplification and expression of the HMGIC gene in a benign endometrial polyp
In a totally benign endometrial polyp, double minute chromosomes were shown to contain an amplified and apparently nonrearranged… 
1997
1997
HMGIC expressed in a uterine leiomyoma with a deletion of the long arm of chromosome 7 along with a 12q14-15 rearrangement but not in tumors showing del(7) as the sole cytogenetic abnormality.
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