HLA-B27 Antigen

Known as: hla b27, HLA-B27, antigen hla b27 
A specific HLA-B surface antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*27 allele family.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Ankylosing spondylitis is a common form of inflammatory arthritis predominantly affecting the spine and pelvis that occurs in… (More)
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Highly Cited
2011
Highly Cited
2011
CD4 Th cells producing the proinflammatory cytokine IL-17 (Th17) have been implicated in a number of inflammatory arthritides… (More)
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Highly Cited
2005
Highly Cited
2005
The mechanism by which the MHC class I allele, HLA-B27, contributes to spondyloarthritis pathogenesis is unknown. In contrast to… (More)
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Highly Cited
2002
Highly Cited
2002
Abstract Objective. To investigate differences between HLA-B27– and HLA-B27+ patients with ankylosing spondylitis (AS). Methods… (More)
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Highly Cited
2001
Highly Cited
2001
The immune response to HIV-1 in patients who carry human histocompatibility leukocyte antigen (HLA)-B27 is characterized by an… (More)
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Highly Cited
1998
Highly Cited
1998
OBJECTIVE To determine the overall prevalence of spondylarthropathy (SpA) among whites. METHODS To screen for SpA symptoms… (More)
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Highly Cited
1993
Highly Cited
1993
Ankylosing spondylitis and seronegative spondylarthropathies such as Reiter's syndrome and reactive arthritis are strongly… (More)
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Highly Cited
1991
Highly Cited
1991
A pool of endogenous peptides bound to the human class I MHC molecule, HLA-B27, has been isolated. Microsequence analysis of the… (More)
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Highly Cited
1991
Highly Cited
1991
X-ray crystallography reveals electron density in the antigen-binding site of HLA-B27 that is an interpretable image of nonameric… (More)
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Highly Cited
1987
Highly Cited
1987
Ankylosing spondylitis (AS) and Reiter's syndrome (RS) both show a strong correlation with the HLA B27 haplotype. We studied… (More)
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