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HLA-B27 Antigen

Known as: hla b27, HLA-B27, antigen hla b27 
A specific HLA-B surface antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*27 allele family.
National Institutes of Health

Related topics

Related topics

8 relations
HLA Class I Histocompatibility Antigen, B-27 alpha ChainHLA-B27 Bld Donr QlIn Bloodaspects of radiation effects

Narrower (3)

HLA-B protein, humanHLA-B*27:04 antigenHLA-B*27:05 antigen

Papers overview

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Review
1999
Review
1999
HLA-B27 and disease pathogenesis: new structural and functional insights
The human leukocyte antigen class I allele HLA-B27 is a major histocompatibility complex (MHC) antigen that is strongly… 
Highly Cited
1998
Highly Cited
1998
Association of different tumor necrosis factor alpha promoter allele frequencies with ankylosing spondylitis in HLA-B27 positive individuals.
OBJECTIVE To investigate the potential association of tumor necrosis factor alpha (TNFalpha) promoter alleles with ankylosing… 
Highly Cited
1998
Highly Cited
1998
Spontaneous inflammatory disease in HLA-B27 transgenic mice is independent of MHC class II molecules: a direct role for B27 heavy chains and not B27-derived peptides.
Although association of HLA-B27 with human spondyloarthropathies has been known for several years, its role in disease… 
Highly Cited
1998
Highly Cited
1998
An HLA-B27 polymorphism (B*2710) that is critical for T-cell recognition has limited effects on peptide specificity.
The B*2710 subtype differs from the HLA-B27 prototype (B*2705) only by having Glu instead of Val at position 152, in the alpha2… 
Highly Cited
1998
Highly Cited
1998
The same natural ligand is involved in allorecognition of multiple HLA-B27 subtypes by a single T cell clone: role of peptide and the MHC molecule in alloreactivity.
The human alloreactive CTL clone 27S69, raised against B*2705, cross-reacts with B*2702 and B*2703, but not with B*2701, B*2704… 
Highly Cited
1992
Highly Cited
1992
Genetic modulation of antigen presentation by HLA-B27 molecules
In studies of antigenic peptide presentation, we have found a healthy volunteer whose lymphoblastoid cells were unable to present… 
Highly Cited
1990
Highly Cited
1990
Structural homologies between two HLA B27-restricted peptides suggest residues important for interaction with HLA B27.
Recently we described an HLA B27-restricted peptide derived from HIV gag p24 protein. In this study we have isolated an HLA B27… 
1985
1985
Primary structure of papain-solubilized human histocompatibility antigen HLA-B27.
The complete amino acid sequence of papain-solubilized HLA-B27, an antigen that presents a very strong association to the… 
Highly Cited
1982
Highly Cited
1982
Subtypes of HLA-B27 detected by cytotoxic T lymphocytes and their role in self-recognition.
Highly Cited
1981
Highly Cited
1981
MONOCLONAL ANTI-HLA-B27 ANTIBODY (B27M1): PRODUCTION AND LACK OF DETECTABLE TYPING DIFFERENCE BETWEEN PATIENTS WITH ANKYLOSING SPONDYLITIS, REITER'S SYNDROME, AND NORMAL CONTROLS
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