HKH40A

HKH40A, the 8-methoxy analog of WMC79, is a synthetic agent with promising in vitro and in vivo antitumor activity, especially… Expand

Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA HKH40A is a synthetic, DNA-intercalating (Kosakowska… Expand

HKH40A (RTA 502), or 5-nitro-2-(3-{4-[3-(8-methoxy-6-oxo-6H-2,10b-diaza-aceanthrylen-5-ylamino)propyl]piperazin-1-yl}-propyl)-2… Expand

HKH40A (RTA 502), an optimized 8-methoxy analog of the unsymmetrical bifunctional antitumor agent WMC79, was found to be potently… Expand

Unsymmetrical bifunctional antitumor agent WMC79 was further optimized to generate compound 7b that not only inhibited the growth… Expand