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HFA 227

Known as: HFA-227 
National Institutes of Health

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1 relation

Broader (1)

apaflurane

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Isothermal calorimetry: a predictive tool to model drug-propellant interactions in pressurized metered dose systems.
2013
2013
Reformulation of Stmerin® D CFC formulation using HFA propellants
Stmerin® D was reformulated using hydrofluoroalkanes (HFA-134a and HFA-227) as alternative propellants instead of… 
2006
2006
Effect of the moisture content in aerosol on the spray performance of Stmerin D HFA preparations.
Stmerin D, a pressurized metered dose inhaler (MDI) for treatment of asthma, contains CFCs (chlorofluorocarbons) as a propellant… 
2004
2004
Influence of the Valve Lubricant on the Aerodynamic Particle Size of a Metered Dose Inhaler
Presented in this work are the results of a study designed to investigate the impact of valve lubricant (i.e., silicone oil) on… 
2003
2003
Influence of the Storage Orientation on the Aerodynamic Particle Size of a Suspension Metered Dose Inhaler Containing Propellant HFA-227
Abstract Presented in this work are the results of a study designed to investigate the impact of the storage position on the… 
2000
2000
An investigation of the solubility of various compounds in the hydrofluoroalkane propellants and possible model liquid propellants.
The aims of this study were to investigate descriptive parameters that may predict the solubility of compounds in the… 
1998
1998
Tolerability and in vivo performance of a novel freon-free metered dose inhaler for a fixed combinational product of reproterol and disodium cromoglycate.
The present study was conducted to describe and compare the in vivo performance (systemic exposure), clinical and laboratory… 
1997
1997
The technical transition to CFC-free inhalers.
Pressurised metered dose inhalers (pMDIs) provide essential therapy for a large proportion of the 70 million people in the world… 
Review
1991
Review
1991
Issues surrounding MDI formulation development with non-CFC propellants.
Reformulation of metered-dose inhalers (MDIs) without the use of chlorofluorocarbon (CFC) propellants presents numerous obstacles… 
Review
1991
Review
1991
CFC replacements: safety testing, approval for use in metered dose inhalers.
HFA-134a and HFA-227 (chlorine free hydrofluoro-alkanes) are at present in extensive nonclinical safety testing sponsored by two… 
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