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HER2 Positive Breast Carcinoma

Known as: HER2 Overexpressing Subtype of Breast Carcinoma, HER2 Overexpressing Breast Carcinoma, HER2 Positive Breast Cancer 
A biologic subset of breast carcinoma defined by high expression of HER2, GRB7, and TRAP100, and by lack of expression of estrogen receptor (ER).
National Institutes of Health

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AC-T-T RegimenBreastEpithelial CellsEpithelium

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Combination of lapatinib with isothiocyanates overcomes drug resistance and inhibits migration of HER2 positive breast cancer cells
BackgroundLapatinib is a commonly used drug that interrupts signaling from the epidermal growth factor receptors, EGFR and HER2… 
2015
2015
Obesity-associated microRNA-26b regulates the proliferation of human preadipocytes via arrest of the G1/S transition.
MicroRNAs (miRNAs) are short, 20‑24 nucleotide non‑coding RNAs, which are involved in multiple biological processes, including… 
2014
2014
p53 Modulates Hsp90 ATPase Activity and Regulates Aryl Hydrocarbon Receptor Signaling
The aryl hydrocarbon receptor (AhR), a client protein of heat shock protein 90 (Hsp90), is a ligand-activated transcription… 
2013
2013
PTEN, Akt, MAPK, p53 and p95 expression to predict trastuzumab resistance in HER2 positive breast cancer.
PURPOSE Mutations that activate the PIK3CA oncogene and inhibit the tumor suppressor gene PTEN action are commonly found in… 
Review
2010
Review
2010
Zinc finger protein 521, a new player in bone formation
Exploration of anabolic pathways in osteoblasts revealed that Zfp521, a 30‐zinc finger protein, is highly expressed at the… 
2010
2010
The effects of parkin suppression on the behaviour, amyloid processing, and cell survival in APP mutant transgenic mice
2010
2010
Prognostic effect of hormone receptor status in early HER2 positive breast cancer patients.
Review
2009
Review
2009
The role of opiorphins (endogenous neutral endopeptidase inhibitors) in urogenital smooth muscle biology.
INTRODUCTION The opiorphins are a newly characterized class of peptides that act as potent endogenous neutral endopeptidase (NEP… 
2004
2004
Randomized phase III study of trastuzumab, paclitaxel, and carboplatin versus trastuzumab and paclitaxel in women with HER-2 overexpressing metastatic breast cancer: An update including survival.
573 Purpose: This randomized multicenter phase III trial evaluated the efficacy and safety of trastuzumab with paclitaxel 175 mg… 
1994
1994
Suppressors of nmtl-181, a conditional lethal allele of the Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase gene, reveal proteins involved in regulating protein N-myristoylation…
Several essential Saccharomyces cerevisiae proteins require myristate to be covalently bound to their amino-terminal glycine for… 
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