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HCT-116

A carcinoma cell line established from an adult male patient with colon carcinoma. HCT-116 cells have a mutation in codon 13 of the ras proto… 
National Institutes of Health

Papers overview

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2017
2017
Involvement of phosphatidylinositide 3-kinase pathway in the resistant mechanisms against benzyl isothiocyanate in human colorectal cancer cells
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2017
2017
Selective cytotoxicity of bioluminescent bacteria isolated from fresh ink of Philippine squid on human colon cancer and normal cell lines
Aims: The current work determined the cytotoxicity of the symbiont bioluminescent bacteria isolated from fresh ink of the squid… 
2016
2016
N 1 , N 3-bis ( 3-methoxysalicylidene ) diethylenetriamine induces apoptosis in colon cancer HCT-116 cells through inhibiting Wnt 1 / β-catenin signaling pathway
Objective: The anti-cancer effect and mechanism of N1,N3-bis(3-methoxysalicylidene) diethylenetriamine (Valdien) in HCT-116 cells… 
2016
2016
H Inhibitory Activity of New Gin-gerol Derivatives as Potential Colorectal Cancer Therapy
2016
2016
Cytotoxic Compounds from Dysoxylum gaudichaudianum ( A . Juss . ) Miq .
Squalene (1), polyprenol (2), triglycerides (3), and β-sitosterol (4), isolated from the dichloromethane extract of the leaves of… 
2015
2015
C 6 ceramide dramatically increases vincristine sensitivity both in vivo and in vitro , involving AMP-activated protein kinase – p 53 signaling
Use of the conventional cancer chemotherapy (i.e. vincristine) is limited in tumor cells exhibiting pre-existing or acquired… 
2014
2014
HY-2, a novel DNA topoisomerase II inhibitor, induces G2/M cell cycle arrest in HCT-116 cells
Abstract 4beta-(Benzoylthioureido)-4′-demethyl-4-desoxypodophyllotoxin (HY-2), a synthetic aroylthiourea analog of… 
2014
2014
Resistin Effect on HCT-116 Colorectal Cancer Cells Proliferation and Telomer- ase Expression
Background: The plasma concentration of resistin, an adipokine, and its expression are increased significantly in patients with… 
2011
2011
Rhein induces apoptosis of HCT-116 human colon cancer cells via activation of the intrinsic apoptotic pathway
Rhein, a major compound in rhubarb, has been found to have anti-tumor properties in many human cancer cells. However, the details… 
2010
2010
Experimental Study on Effect of Compounds in Inhibiting HCT-116 Human Colon Cancer Cells: The Preliminary Results
Objective. Several compounds were studied for their growth inhibitory effects on cultured HCT-116 human colon cancer cells…