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HCAR2 gene

Known as: HM74B, HYDROXYCARBOXYLIC ACID RECEPTOR 2, HCAR2 
 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Diet and the gut microbiota may underpin numerous human diseases. A major metabolic product of commensal bacteria are short-chain… Expand
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Highly Cited
2014
Highly Cited
2014
Commensal gut microflora and dietary fiber protect against colonic inflammation and colon cancer through unknown targets… Expand
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Review
2014
Review
2014
There is now an abundance of evidence to show that short-chain fatty acids (SCFAs) play an important role in the maintenance of… Expand
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Highly Cited
2009
Highly Cited
2009
Short-chain fatty acids, generated in colon by bacterial fermentation of dietary fiber, protect against colorectal cancer and… Expand
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Review
2008
Review
2008
Pharmacological doses of nicotinic acid induce a profound change in the plasma levels of various lipids and lipoproteins. The… Expand
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Highly Cited
2008
Highly Cited
2008
G protein-coupled receptor (GPR)109A (HM74A) is a Gi protein-coupled receptor, which is activated by nicotinic acid (NA), a lipid… Expand
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Highly Cited
2006
Highly Cited
2006
Nicotinic acid, used for atherosclerosis treatment, has an adverse effect of skin flushing. The flushing mechanism, thought to be… Expand
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Highly Cited
2005
Highly Cited
2005
Nicotinic acid (niacin) has long been used as an antidyslipidemic drug. Its special profile of actions, especially the rise in… Expand
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Highly Cited
2005
Highly Cited
2005
As a treatment for dyslipidemia, oral doses of 1–3 grams of nicotinic acid per day lower serum triglycerides, raise high density… Expand
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Highly Cited
2003
Highly Cited
2003
Nicotinic acid has been used clinically for over 40 years in the treatment of dyslipidemia producing a desirable normalization of… Expand
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