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HCAR2 gene

Known as: HM74B, HYDROXYCARBOXYLIC ACID RECEPTOR 2, HCAR2 
National Institutes of Health

Related topics

Related topics

3 relations
GPR109B wt AlleleHCAR3 gene

Broader (1)

Genes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Gut microbiota and hypertension
Recently, attention has been focused on the potential importance of gut microbiota (GM) in human health. GM is considered to play… 
Review
2016
Review
2016
Niacin Alternatives for Dyslipidemia: Fool’s Gold or Gold Mine? Part II: Novel Niacin Mimetics
Two cardiovascular outcome trials established niacin 3 g daily prevents hard cardiac events. However, as detailed in part I of… 
Review
2014
Review
2014
A novel treatment target for Parkinson's disease
2012
2012
Identification and Characterization of Distinct C-Terminal Domains of the Human Hydroxycarboxylic Acid Receptor-2 That Are Essential for Receptor Export, Constitutive Activity, Desensitization, and…
The human hydroxycarboxylic acid receptor 2 (HCA2), also known as GPR109A and HM74a, was first identified as a niacin receptor… 
2012
2012
Niacin inhibits skin dendritic cell mobilization in a GPR109A independent manner but has no impact on monocyte trafficking in atherosclerosis.
Highly Cited
2010
Highly Cited
2010
Modulation of HDL metabolism by the niacin receptor GPR109A in mouse hepatocytes.
2010
2010
Evidence for constitutive dimerization of niacin receptor subtypes.
2007
2007
Fluorinated pyrazole acids are agonists of the high affinity niacin receptor GPR109a.
2007
2007
Agonist lead identification for the high affinity niacin receptor GPR109a.
2006
2006
Human epidermoid A431 cells express functional nicotinic Acid receptor HM74a
Nicotinic acid (niacin) has been used clinically to manage dyslipidemia for many years. The molecular target of nicotinic acid… 
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