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HCAR2 gene

Known as: HM74B, HYDROXYCARBOXYLIC ACID RECEPTOR 2, HCAR2 
National Institutes of Health

Related topics

Related topics

3 relations
GPR109B wt AlleleHCAR3 gene

Broader (1)

Genes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Overexpressing human GPR109A leads to pronounced reduction in plasma triglyceride levels in BAC transgenic rats.
2017
2017
AMP010014A09 in Sus Scrofa Encodes an Analog of G Protein-Coupled Receptor 109A, Which Mediates the Anti-Inflammatory Effects of Beta-Hydroxybutyric Acid
Background: Hydroxy-carboxylic acid receptor 2 (HCA2, also called GPR109A) belongs to the G protein-coupled receptor (GPCR… 
2012
2012
Niacin inhibits skin dendritic cell mobilization in a GPR109A independent manner but has no impact on monocyte trafficking in atherosclerosis.
2012
2012
Identification and Characterization of Distinct C-Terminal Domains of the Human Hydroxycarboxylic Acid Receptor-2 That Are Essential for Receptor Export, Constitutive Activity, Desensitization, and…
The human hydroxycarboxylic acid receptor 2 (HCA2), also known as GPR109A and HM74a, was first identified as a niacin receptor… 
2011
2011
Study of GPR 81 , the Lactate Receptor , from Distant Species Identifies Residues and Motifs Critical for GPR 81 Functions
Receptors from distant species may have conserved functions despite significant differences in protein sequences. Whereas the… 
2011
2011
Metabolism of [14C]GSK977779 in Rats and Its Implication with the Observed Covalent Binding
GSK977779 is a potent HM74a agonist evaluated for the treatment of dyslipidemia. The disposition and metabolism of [14C]GSK977779… 
2010
2010
Pyrido pyrimidinones as selective agonists of the high affinity niacin receptor GPR109A: optimization of in vitro activity.
Review
2009
Review
2009
HM74a agonists: will they be the new generation of nicotinic acid?
The discovery of HM74a as a high affinity receptor for nicotinic acid has opened up new areas for investigation. Since its… 
2007
2007
Fluorinated pyrazole acids are agonists of the high affinity niacin receptor GPR109a.
2007
2007
Agonist lead identification for the high affinity niacin receptor GPR109a.
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