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H 142
Known as:
H-142
, L-Lysine, N2-(N-(N-(N-(4-methyl-2-((N-(N-(1-(N-L-prolyl-L-histidyl)-L-prolyl)-L-phenylalanyl)-L-histidyl)amino)pentyl)-L-valyl)-L-isoleucyl)-L-histidyl)-, (S)-
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Angiotensinogen
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1993
Highly Cited
1993
2-substituted quinoline alkaloids as potential antileishmanial drugs
A. Fournet
,
A. A. Barrios
,
V. Muñoz
,
R. Hocquemiller
,
A. Cavé
,
J. Bruneton
Antimicrobial Agents and Chemotherapy
1993
Corpus ID: 25899531
Ten 2-substituted quinoline alkaloids isolated from a plant used for treatment of New World cutaneous leishmaniasis have…
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1991
1991
Vascular production and regulation of angiotensin.
K. Hilgers
,
J. Mann
,
U. Hilgenfeldt
,
D. Ganten
Blood & Vessel
1991
Corpus ID: 12855082
To test the hypothesis that angiotensin (Ang) I and II are produced by blood vessels, we investigated the formation of both Ang I…
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Highly Cited
1989
Highly Cited
1989
Angiotensin formation in the isolated rat hindlimb.
K. Hilgers
,
M. Kuczera
,
+4 authors
J. Mann
Journal of Hypertension
1989
Corpus ID: 23304891
Local vascular generation of angiotensin was investigated in isolated perfused rat hindquarters. Extraction and combined high…
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Highly Cited
1987
Highly Cited
1987
High resolution X-ray analyses of renin inhibitor-aspartic proteinase complexes
S. Foundling
,
J. Cooper
,
+16 authors
M. Szelke
Nature
1987
Corpus ID: 4274851
Inhibitors of the conversion of angiotensinogen to the vasoconstrictor angiotensin II have considerable value as antihypertensive…
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1985
1985
Energy calculations on aspartic proteinases: human renin, endothiapepsin and its complex with an angiotensinogen fragment analogue, H-142.
A. Hemmings
,
S. Foundling
,
B. L. Sibanda
,
S. Wood
,
L. Pearl
,
T. Blundell
Biochemical Society Transactions
1985
Corpus ID: 7291166
The rational design of inhibitors of human renin for the treatment of hypertension depends on a detailed knowledge of the renin…
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1985
1985
Design, synthesis and analysis of new synthetic substrates for the aspartic proteinases.
B. Dunn
,
J. Kay
Biochemical Society Transactions
1985
Corpus ID: 27369640
certainty although its general position is reasonably well defined. In the energy refinement, this part of the structure…
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1984
1984
Angiotensin I-generating acid endopeptidase activity in neurosecretory vesicles isolated from bovine pituitary
H. Gainer
,
J. Russell
,
Y. Loh
Neuropeptides
1984
Corpus ID: 25682202
1983
1983
REDUCTION OF BLOOD PRESSURE IN MAN WITH H-142, A POTENT NEW RENIN INHIBITOR
D. Webb
,
A. Cumming
,
+5 authors
B. Donovan
The Lancet
1983
Corpus ID: 7225723
1983
1983
Inhibition of renin in the primate Callithrix jacchus (common marmoset).
K. Hofbauer
,
J. Ménard
,
J. Michel
,
J. Wood
Clinical and Experimental Hypertension Part A…
1983
Corpus ID: 43709533
The effects of an antiserum against human kidney renin and of H-142, a peptide inhibitor of human renin, were studied in the…
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Highly Cited
1982
Highly Cited
1982
Potent new inhibitors of human renin
M. Szelke
,
B. Leckie
,
+4 authors
A. F. Lever
Nature
1982
Corpus ID: 4306900
The renal acid protease renin selectively cleaves its plasma substrate angiotensinogen to release the decapeptide angiotensin I…
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