Guanidinoacetate N-Methyltransferase

Known as: Guanidinoacetate N-Methyltransferase [Chemical/Ingredient], GA Methyltransferase, Guanidinoacetate N Methyltransferase 
This enzyme catalyzes the last step of CREATINE biosynthesis by catalyzing the METHYLATION of guanidinoacetate to CREATINE.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Guanidinoacetate methyltransferase (GAMT) deficiency is a disorder of creatine biosynthesis, characterized by excessive amounts… (More)
  • figure 1
  • table 1
  • table 2
  • table 3
  • table 4
Is this relevant?
2006
2006
Prospective observation in a neonate with guanidinoacetate methyltransferase deficiency (GAMT-D), a severe neurometabolic… (More)
Is this relevant?
Highly Cited
2004
Highly Cited
2004
We generated a knockout mouse model for guanidinoacetate N-methyltransferase (GAMT) deficiency (MIM 601240), the first discovered… (More)
Is this relevant?
Review
2002
Review
2002
Major achievements made over the last several years have highlighted the important roles of creatine and the creatine kinase… (More)
Is this relevant?
2002
2002
Guanidinoacetate methyltransferase (GAMT) is the enzyme that catalyzes the last step of creatine biosynthesis. The enzyme is… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
This paper reports clinical and metabolic studies of two Italian siblings with a novel form of persistent isolated… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Hepatic guanidinoacetate methyltransferase deficiency induces a deficiency of creatine/phosphocreatine in muscle and brain and an… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
1997
1997
The first inborn error of creatine metabolism (guanidinoacetate methyltransferase [GAMT] deficiency) has recently been recognized… (More)
  • table 1
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
1996
Highly Cited
1996
In two children with an accumulation of guanidinoacetate in brain and a deficiency of creatine in blood, a severe deficiency of… (More)
Is this relevant?
Highly Cited
1996
Highly Cited
1996
BACKGROUND The creatine/creatine-phosphate system is essential for the storage and transmission of phosphate-bound energy in… (More)
Is this relevant?