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GsMTx-4

 
National Institutes of Health

Related topics

Related topics

1 relation
MTx4 protein, Grammostola spatulata

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Stretch-activated ion channel Piezo1 directs lineage choice in human neural stem cells
Significance Stem cells make lineage-choice decisions based on a combination of internal and external signals, including… Expand
Highly Cited
2013
Highly Cited
2013
Nonspecific sarcolemmal cation channels are critical for the pathogenesis of malignant hyperthermia
Malignant hyperthermia (MH) susceptibility has been attributed to a leaky sarcoplasmic reticulum (SR) caused by missense… Expand
2011
2011
Stretch induced endothelin-1 secretion by adult rat astrocytes involves calcium influx via stretch-activated ion channels (SACs).
The expression of endothelins (ETs) and ET-receptors is often upregulated in brain pathology. ET-1, a potent vasoconstrictor… Expand
2010
2010
Hypoxia Activates a Ca2+-Permeable Cation Conductance Sensitive to Carbon Monoxide and to GsMTx-4 in Human and Mouse Sickle Erythrocytes
Background Deoxygenation of sickle erythrocytes activates a cation permeability of unknown molecular identity (Psickle), leading… Expand
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Highly Cited
2009
Highly Cited
2009
TRPC1 and TRPC6 Channels Cooperate with TRPV4 to Mediate Mechanical Hyperalgesia and Nociceptor Sensitization
The transient receptor potential vanilloid 4 (TRPV4) contributes to mechanical hyperalgesia of diverse etiologies, presumably as… Expand
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Highly Cited
2008
Highly Cited
2008
Hypoosmotic‐ and pressure‐induced membrane stretch activate TRPC5 channels
Transient receptor potential (TRP) channels mediate a wide array of sensory functions. We investigated the role of TRPC5, a… Expand
Highly Cited
2007
Highly Cited
2007
High-Threshold Mechanosensitive Ion Channels Blocked by a Novel Conopeptide Mediate Pressure-Evoked Pain
Little is known about the molecular basis of somatosensory mechanotransduction in mammals. We screened a library of peptide… Expand
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Highly Cited
2007
Highly Cited
2007
TRPA1 Is Differentially Modulated by the Amphipathic Molecules Trinitrophenol and Chlorpromazine*
TRPA1, a poorly selective Ca2+-permeable cation channel, is expressed in peripheral sensory neurons, where it is considered to… Expand
Highly Cited
2006
Highly Cited
2006
A common mechanism underlies stretch activation and receptor activation of TRPC6 channels
The TRP family of ion channels transduce an extensive range of chemical and physical signals. TRPC6 is a receptor-activated… Expand
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2006
2006
Lipid membrane interaction and antimicrobial activity of GsMTx-4, an inhibitor of mechanosensitive channel.
GsMTx-4, a polypeptide from the spider Grammostola spatulata, is an inhibitor of mechanosensitive channels. It is known to… Expand
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