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Gleason Pattern 4 (classification)

Known as: Gleason Grade 4, Gleason Pattern 4 
A pattern of prostate carcinoma characterized by the presence of fused, cribriform, or poorly defined glands. There is partial loss of normal… 
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Absolute percentage of biopsied tissue positive for Gleason pattern 4 disease (APP4) appears predictive of disease control after high dose rate brachytherapy and external beam radiotherapy in…
2018
2018
Prostate Cancers Detected by Magnetic Resonance Imaging-Targeted Biopsies Have a Higher Percentage of Gleason Pattern 4 Component and Are Less Likely to Be Upgraded in Radical Prostatectomies.
CONTEXT.— In Gleason score (GS) 7 prostate cancers, the quantity of Gleason pattern 4 (GP 4) is an important prognostic factor… 
2018
2018
Prostate cancer grading in 2018: limitations, implementations, cribriform morphology, and biological markers
The Gleason grading system is among the most important prognostic factors in patients with prostate cancer. From the 2005 to the… 
2017
2017
SOCS3 Immunohistochemical Expression Seems to Support the 2005 and 2014 International Society of Urological Pathology (ISUP) Modified Gleason Grading System
In the 2014, The International Society of Urological Pathology (ISUP) consensus conference update the grading of prostate, last… 
2014
2014
Primary Gleason pattern in biopsy Gleason score 7 is predictive of adverse histopathological features and biochemical failure following radical prostatectomy
Abstract Objective. The aim of this study was to analyse whether primary Gleason pattern in biopsy Gleason score (GS) 7 predicted… 
Review
2010
Review
2010
The use of immunohistochemistry for diagnosis of prostate cancer.
PURPOSE Atypical glands (ASAP) are diagnosed in 5.0% of prostate biopsies, and cancer identification in a rebiopsy is higher than… 
2009
2009
Three-dimensional microscopic image reconstruction of prostatic adenocarcinoma.
CONTEXT Routine microscopy provides only a 2-dimensional view of the complex 3-dimensional structure that makes up human tissue… 
Review
2007
Review
2007
The proportion of prostate biopsy tissue with Gleason pattern 4 or 5 predicts for biochemical and clinical outcome after radiotherapy for prostate cancer.
2005
2005
O padrão 4 de Gleason e o volume tumoral no prognóstico do carcinoma da próstata
INTRODUCTION: Early introduction of adjuvant radiation or hormone therapy after radical prostatectomy has been advocated in… 
1998
1998
The value of the ratio of free-to-total prostate specific antigen for staging purposes in previously untreated prostate cancer.
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