Giant Cells

Known as: Cells, Giant, Multinucleated Giant Cells, Polykaryocytes 
Multinucleated masses produced by the fusion of many cells; often associated with viral infections. In AIDS, they are induced when the envelope… (More)
National Institutes of Health

Related topics

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Anaplastic Giant Cell Thyroid CarcinomaCDISC SEND Non-Neoplastic Finding Type TerminologyCarcinoma, Giant CellCardiac Malignant Fibrous Histiocytoma
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Papers overview

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Review
2016
Review
2016
How does adenosine control neuronal dysfunction and neurodegeneration?
The adenosine modulation system mostly operates through inhibitory A1 (A1 R) and facilitatory A2A receptors (A2A R) in the brain… (More)
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Highly Cited
2010
Highly Cited
2010
Denosumab in patients with giant-cell tumour of bone: an open-label, phase 2 study.
BACKGROUND Giant-cell tumour (GCT) of bone is a primary osteolytic bone tumour with low metastatic potential and is associated… (More)
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Highly Cited
2005
Highly Cited
2005
Melanopsin-expressing ganglion cells in primate retina signal colour and irradiance and project to the LGN
Human vision starts with the activation of rod photoreceptors in dim light and short (S)-, medium (M)-, and long (L)- wavelength… (More)
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Highly Cited
2005
Highly Cited
2005
Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans.
Macrophage infiltration of white adipose tissue (WAT) is implicated in the metabolic complications of obesity. The precipitating… (More)
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Highly Cited
1997
Highly Cited
1997
Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy.
Although highly active antiretroviral therapy (HAART) in the form of triple combinations of drugs including protease inhibitors… (More)
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Highly Cited
1996
Highly Cited
1996
HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5
The β-chemokines MIP-1α, MIP-1β and RANTES inhibit infection of CD4+ cells by primary, non-syncytium-inducing (NSI) HIV-1 strains… (More)
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Highly Cited
1996
Highly Cited
1996
The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1
A putative chemokine receptor that we previously cloned and termed LESTR has recently been shown to function as a co-receptor… (More)
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Highly Cited
1996
Highly Cited
1996
A Dual-Tropic Primary HIV-1 Isolate That Uses Fusin and the β-Chemokine Receptors CKR-5, CKR-3, and CKR-2b as Fusion Cofactors
Here, we show that the beta-chemokine receptor CKR-5 serves as a cofactor for M-tropic HIV viruses. Expression of CKR-5 with CD4… (More)
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Highly Cited
1990
Highly Cited
1990
The American College of Rheumatology 1990 criteria for the classification of giant cell arteritis.
Criteria for the classification of giant cell (temporal) arteritis were developed by comparing 214 patients who had this disease… (More)
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Highly Cited
1952
Highly Cited
1952
The dual effect of membrane potential on sodium conductance in the giant axon of Loligo.
This paper contains a further account of the electrical properties of the giant axon of Loligo. It deals with the 'inactivation… (More)
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