Genz 123346

Known as: Genz-123346, Genz123346 
 
National Institutes of Health

Papers overview

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2018
2018
RATIONALE Tetraspanins are cell membrane-spanning proteins that transduce extracellular signals and control cell adhesion via… (More)
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2015
2015
Central nervous regulation of body weight and adipose tissue function is mainly conducted by hypothalamic neurons. Neuronal… (More)
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2011
2011
Glucosylceramide synthase (GCS) is a key enzyme engaged in the biosynthesis of glycosphingolipids and in regulating ceramide… (More)
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Highly Cited
2010
Highly Cited
2010
Polycystic kidney disease (PKD) represents a family of genetic disorders characterized by renal cystic growth and progression to… (More)
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Review
2010
Review
2010
Summary of key findings Glucosylceramide (GlcCer) levels were found to be higherin kidney tissue of autosomal dominant PKD… (More)
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2010
2010
Glucosylceramide (GlcCer) levels were found to be higher in kidney tissue of autosomal dominant PKD/conditional knockout mice and… (More)
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2009
2009
Objectives and background The iminosugar N-(5-adamantane-1-ylmethoxy)pentyl-1-deoxynojirimycin (AMPDNM) potently controls… (More)
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Highly Cited
2007
Highly Cited
2007
Previous reports have shown that glycosphingolipids can modulate the activity of the insulin receptor, and studies in transgenic… (More)
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