Genetic Load

Known as: Load, Genetic 
The relative amount by which the average fitness of a POPULATION is lowered, due to the presence of GENES that decrease survival, compared to the… (More)
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Among the fundamental evolutionary forces, recombination arguably has the largest impact on the practical work of plant breeders… (More)
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Highly Cited
2014
Highly Cited
2014
The domestication of the horse ∼ 5.5 kya and the emergence of mounted riding, chariotry, and cavalry dramatically transformed… (More)
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Highly Cited
2013
Highly Cited
2013
Mutations are the ultimate source of heritable variation for evolution. Understanding how mutation rates themselves evolve is… (More)
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Highly Cited
2005
Highly Cited
2005
The role of genetic factors in extinction is firmly established for diploid organisms, but haplodiploids have been considered… (More)
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Review
2005
Review
2005
During the past three to four decades, the incidence of acquired sensorineural hearing loss (SNHL) in children living in more… (More)
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Highly Cited
2003
Highly Cited
2003
As the central component of the human endotoxin sensor, Toll-like receptor 4 (TLR4) functions in the early detection and response… (More)
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Highly Cited
1999
Highly Cited
1999
We introduce and analyze a general model of a population evolving over a network of selectively neutral genotypes. We show that… (More)
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1998
1998
It has been hypothesized that natural selection reduces the "genetic load" of deleterious alleles from populations that inbreed… (More)
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Highly Cited
1991
Highly Cited
1991
"THE effects of inbreeding may not be as noticeable in the first generation as the invigoration immediately apparent after… (More)
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Highly Cited
1988
Highly Cited
1988
The data base of an ongoing population-based registry with multiple sources of ascertainment was used to estimate the present… (More)
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