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Genes, vpu

Known as: Gene, vpu, vpu Gene, vpu Genes 
DNA sequences that form the coding region for the HIV-1 regulatory protein vpu (viral protein U) that greatly increases the export of virus particles… 
National Institutes of Health

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2 relations
aspects of radiation effectsphysiological aspects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
A formidable challenge
Better understanding of HIV biology, virus-host interactions and mechanisms of an efficient immune response advance efforts for… 
2013
2013
Identification of novel key amino acids at the interface of the transmembrane domains of human BST-2 and HIV-1 Vpu
BackgroundBST-2 (bone marrow stromal cell antigen 2) is an interferon-inducible protein that inhibits virus release by tethering… 
2011
2011
Some Human Immunodeficiency Virus Type 1 Vpu Proteins Are Able To Antagonize Macaque BST-2 In Vitro and In Vivo: Vpu-Negative Simian-Human Immunodeficiency Viruses Are Attenuated In Vivo
ABSTRACT Human immunodeficiency virus type 1 (HIV-1) Vpu enhances the release of viral particles from infected cells by targeting… 
2007
2007
High frequency of defective vpu compared with tat and rev genes in brain from patients with HIV type 1-associated dementia.
Human immunodeficiency virus type 1 (HIV) infection of the central nervous system frequently causes HIV-associated dementia (HAD… 
2002
2002
Characterization of pol, vif, vpr, and vpu genes of HIV type 1 in AIDS patients with high viral load and stable CD4+ T cell counts on combination therapy.
The success of combination therapy has also led to AIDS patients who exhibit elevated viral load without a corresponding decline… 
2001
2001
Growth characteristics of SHIV without the vpu gene.
NM-3 is a prototype of chimeric virus between simian and human immunodeficiency viruses (SHIV). It grows in monkey lymphocytic… 
Highly Cited
1997
Highly Cited
1997
Putative alpha-helical structures in the human immunodeficiency virus type 1 Vpu protein and CD4 are involved in binding and degradation of the CD4 molecule
The human immunodeficiency virus type 1 (HIV-1) vpu gene encodes a 16-kDa class I integral membrane phosphoprotein with an N… 
1997
1997
Inhibition of prokaryotic cell growth by HIV1 Vpr.
1997
1997
Gross defects in the vpr and vpu genes of HIV type 1 cannot explain the differences in RNA copy number between long-term asymptomatics and progressors.
Disease progression in HIV-1-infected individuals is strongly associated with persistent and high numbers of HIV-1 RNA copies. We… 
Highly Cited
1995
Highly Cited
1995
Degradation of CD4 induced by human immunodeficiency virus type 1 Vpu protein: a predicted alpha-helix structure in the proximal cytoplasmic region of CD4 contributes to Vpu sensitivity.
The HIV-1-encoded Vpu protein induces a rapid and specific degradation of CD4 molecules in the endoplasmic reticulum (ER). In… 
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