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Genes, Immediate-Early

Known as: Immediate Early Genes, Immediate-Early Gene, immediate early gene 
Genes that show rapid and transient expression in the absence of de novo protein synthesis. The term was originally used exclusively for viral genes… 
National Institutes of Health

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Genes, RegulatorImmediate-Early Proteinsaspects of radiation effectsphysiological aspects

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IER2 gene

Papers overview

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2001
2001
Expression of an immediate early gene, IEX-1, in human tissues
Abstract. IEX-1 is an immediate early gene that is induced by ionizing radiation, ultraviolet radiation, and a variety of growth… 
Highly Cited
1998
Highly Cited
1998
Raf and Fibroblast Growth Factor Phosphorylate Elk1 and Activate the Serum Response Element of the Immediate Early Genepip92 by Mitogen-Activated Protein Kinase-Independent as Well as -Dependent…
ABSTRACT Previous studies have shown that a mitogen activated protein (MAP) kinase (MEK)-independent signaling pathway is… 
Highly Cited
1996
Highly Cited
1996
Regionally and temporally distinct patterns of induction of c-fos, c-jun and junB mRNAs following experimental brain injury in the rat.
Highly Cited
1994
Highly Cited
1994
The nuclear localization signal of NGFI-A is located within the zinc finger DNA binding domain.
Highly Cited
1994
Highly Cited
1994
Extracellular ATP induces immediate-early gene expression but not cellular hypertrophy in neonatal cardiac myocytes.
It is well-documented that norepinephrine (NE) induces the expression of immediate-early genes (IEGs), such as c-fos, c-jun, and… 
1993
1993
Analysis of the rhesus cytomegalovirus immediate-early gene promoter.
A cytomegalovirus (CMV) isolate has been recovered from a rhesus macaque (Macaca mulatta) experimentally infected with simian… 
Highly Cited
1992
Highly Cited
1992
A novel 7-nucleotide motif located in 3' untranslated sequences of the immediate-early gene set mediates platelet-derived growth factor induction of the JE gene
A cohort of the serum and growth factor regulated immediate-early gene set is induced with slower kinetics than c-fos. Two of the… 
Highly Cited
1991
Highly Cited
1991
Synaptic Regulation of Immediate Early Gene Expression in Primary Cultures of Cortical Neurons
Abstract: Neuronal stimulation can rapidly activate several immediate early genes that code for transcription factors. We have… 
Highly Cited
1986
Highly Cited
1986
Analysis of DNA sequences which regulate the transcription of herpes simplex virus immediate early gene 3: DNA sequences required for enhancer-like activity and response to trans-activation by a…
The far upstream region of herpes simplex virus (HSV) immediate early (IE) gene 3 has previously been shown to increase gene… 
Highly Cited
1982
Highly Cited
1982
DNA sequence analysis of an immediate-early gene region of the herpes simplex virus type 1 genome (map coordinates 0.950 to 0.978).
The nucleotide sequence of 4 kilobases of DNA from within the short region of the genome of herpes simplex virus type 1 has been… 
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