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Gendicine

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Oncolytic Viruses for Tumor Precision Imaging and Radiotherapy.
In 2003 in China, Peng et al. invented the recombinant adenovirus expressing p53 (Gendicine) for clinical tumor virotherapy. This… 
Highly Cited
2013
Highly Cited
2013
Recombinant Human Adenovirus-p53 Injection Induced Apoptosis in Hepatocellular Carcinoma Cell Lines Mediated by p53-Fbxw7 Pathway, Which Controls c-Myc and Cyclin E
F-box and WD repeat domain-containing 7 (Fbxw7/hAgo/hCdc4/Fbw7) is a p53-dependent tumor suppressor and leads to ubiquitination… 
2013
2013
Recombinant adenovirus-p53 (Gendicine) sensitizes a pancreatic carcinoma cell line to radiation.
OBJECTIVE In this study, we examine the effects of recombinant adenovirus-p53 (rAd-p53) on the pancreatic carcinoma cell line… 
Review
2009
Review
2009
Targeted genetic and viral therapy for advanced head and neck cancers.
Review
2009
Review
2009
An update on gene therapy in China.
  • Juan ShiD. Zheng
  • Current opinion in molecular therapeutics (Print)
  • 2009
  • Corpus ID: 11430277
Gene therapy has made significant progress in the past decade, and has strong promise for the treatment of chronic diseases… 
2008
2008
Phase I study of repeated intraepithelial delivery of adenoviral p53 in patients with dysplastic oral leukoplakia.
2006
2006
Controversial Chinese gene-therapy drug entering unfamiliar territory
Experience in clinic is raising issues that Western researchers will not have seen before 
Review
2006
Review
2006
Gendicine's Efficacy: Hard to Translate
CHINESE GENE THERAPYAn English-language review of Chinese gene-therapy clinical trial results has been cited at least a dozen… 
Highly Cited
2005
Highly Cited
2005
Gendicine: The First Commercial Gene Therapy Product; Chinese Translation of Editorial
2004
2004
The genesis of gendicine: The story behind the first gene therapy
In this exclusive interview with BioPharm International, Dr. Zhaohui Peng - CEO and founder of Shenzhen SiBiono GeneTech… 
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