Gelsolin

Known as: Gelsolin Protein, Gelsolin [Chemical/Ingredient], Serum Actin Inhibitory Protein 
A 90-kDa protein produced by macrophages that severs ACTIN filaments and forms a cap on the newly exposed filament end. Gelsolin is activated by… (More)

Topic mentions per year

Topic mentions per year

1967-2017
05019672017

Papers overview

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2006
2006
The chemical environment of the extracellular matrix may influence the tissue-selective deposition observed there in gelsolin… (More)
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2005
2005
Septic shock from bacterial endotoxin, triggered by the release of lipopolysaccharide (LPS) molecules from the outer wall of Gram… (More)
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Highly Cited
1999
Highly Cited
1999
Tuberous sclerosis (TSC) is an autosomal dominant genetic disorder in which benign hamartomas develop in multiple organs, caused… (More)
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Highly Cited
1998
Highly Cited
1998
Rac, a member of the rho family of GTPases, when activated transmits signals leading to actin-based membrane ruffling in… (More)
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Highly Cited
1997
Highly Cited
1997
The caspase-3 (CPP32, apopain, YAMA) family of cysteinyl proteases has been implicated as key mediators of apoptosis in mammalian… (More)
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Highly Cited
1995
Highly Cited
1995
Gelsolin, an 82 kDa actin-binding protein, has potent actin filament-severing activity in vitro. To investigate the in vivo… (More)
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Highly Cited
1993
Highly Cited
1993
The structure of the segment 1 domain of gelsolin, a protein that fragments actin filaments in cells, is reported in complex with… (More)
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Highly Cited
1991
Highly Cited
1991
Increasing the content of the actin-binding protein gelsolin in cultured mouse fibroblasts by up to 125 percent by gene… (More)
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Highly Cited
1987
Highly Cited
1987
The actin-binding protein gelsolin requires micromolar concentrations of calcium ions to sever actin filaments, to potentiate its… (More)
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Highly Cited
1986
Highly Cited
1986
Gelsolin is representative of a class of actin-modulating proteins found in lower eukaryotes to mammals, which sever actin… (More)
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