Ganglioside GM1

Known as: gm1 ganglioside, G(M1) Ganglioside [Chemical/Ingredient], Tetraglycosyl Ceramide, Monosialosyl 
A glycosphingolipid containing a sialic acid residue found in neuronal cell membranes, with potential neuroprotective and neuroregenerative… (More)
National Institutes of Health

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3'-O-sulfo-ganglioside M1bDA-G(M1) gangliosideGM1a MonosialogangliosideLIGA 20
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Ganglioside GM1 Ab.IgM:ACnc:Pt:Ser:QnGanglioside GM1 Ab:PrThr:Pt:Ser:Ord:IFGangliosidosis GM1In Blood
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Papers overview

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Highly Cited
2007
Highly Cited
2007
Gangliosides GM1 and GM3 in the living cell membrane form clusters susceptible to cholesterol depletion and chilling.
Presence of microdomains has been postulated in the cell membrane, but two-dimensional distribution of lipid molecules has been… (More)
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Highly Cited
2005
Highly Cited
2005
Structural membrane alterations in Alzheimer brains found to be associated with regional disease development; increased density of gangliosides GM1 and GM2 and loss of cholesterol in detergent…
The formation of neurotoxic beta-amyloid fibrils in Alzheimer's disease (AD) is suggested to involve membrane rafts and to be… (More)
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Highly Cited
2002
Highly Cited
2002
Interactions of amyloid beta-protein with various gangliosides in raft-like membranes: importance of GM1 ganglioside-bound form as an endogenous seed for Alzheimer amyloid.
GM1 ganglioside-bound amyloid beta-protein (GM1-Abeta), found in brains exhibiting early pathological changes of Alzheimer's… (More)
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Highly Cited
2002
Highly Cited
2002
The size of lipid rafts: an atomic force microscopy study of ganglioside GM1 domains in sphingomyelin/DOPC/cholesterol membranes.
Atomic force microscopy has been used to study the distribution of ganglioside GM1 in model membranes composed of ternary lipid… (More)
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Highly Cited
2001
Highly Cited
2001
Animal model of axonal Guillain-Barré syndrome induced by sensitization with GM1 ganglioside.
Some humans develop the axonal form of Guillain-Barré syndrome after receiving bovine brain ganglioside. On sensitization with… (More)
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Highly Cited
2001
Highly Cited
2001
Cholesterol-dependent formation of GM1 ganglioside-bound amyloid beta-protein, an endogenous seed for Alzheimer amyloid.
GM1 ganglioside-bound amyloid beta-protein (GM1/Abeta), found in brains exhibiting early pathological changes of Alzheimer's… (More)
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Highly Cited
1998
Highly Cited
1998
Galectin-1 is a major receptor for ganglioside GM1, a product of the growth-controlling activity of a cell surface ganglioside sialidase, on human neuroblastoma cells in culture.
Cell density-dependent inhibition of growth and neural differentiation in the human neuroblastoma cell line SK-N-MC are… (More)
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Highly Cited
1995
Highly Cited
1995
Anti-ganglioside GM1 antibodies in Guillain-Barré syndrome and their relationship to Campylobacter jejuni infection.
To clarify the association between Campylobacter jejuni (Cj) infection and antibodies to ganglioside GM1 (anti-GM1) in Guillain… (More)
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Highly Cited
1994
Highly Cited
1994
Ultrastructural localization of gangliosides; GM1 is concentrated in caveolae.
The ultrastructural distribution of the ganglioside GM1 was investigated in A431 cells. After fixation, the cells were frozen in… (More)
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Highly Cited
1994
Highly Cited
1994
The effects of methylprednisolone and the ganglioside GM1 on acute spinal cord injury in rats.
Recent clinical trials have reported that methylprednisolone sodium succinate (MP) or the monosialic ganglioside GM1 improves… (More)
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