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GW843682X

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Tankyrases (TNKS1 and TNKS2) are members of the human poly(ADP-ribose) polymerase (PARP) family and catalyze PARsylation by using… Expand
2016
2016
BACKGROUND GW843682X is a publicly available anti-cancer compound by inhibiting Polo-like kinase. Previous studies revealed that… Expand
2016
2016
In the decades since the introduction of platinum-etoposide, treatment of small cell lung cancer (SCLC) remains virtually… Expand
2013
2013
Polo-like kinases (PLKs) have been reported to be essential components of anti-viral pathways. However, the role of PLKs in the… Expand
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2011
2011
Polo-like kinase 1 (PLK1) is a regulator of mitosis and its upregulation in tumours is often associated with poor prognosis… Expand
2011
2011
AMP-activated protein kinase (AMPK) is being primarily studied as a central metabolic stress sensor, which regulates cell… Expand
2010
2010
  • Zhi Li, T. Umeyama, Ziyin Li, Ching C. Wang
  • Eukaryotic Cell
  • 2010
  • Corpus ID: 24547182
ABSTRACT Polo-like kinase in Trypanosoma brucei (TbPLK) is confined to the flagellum attachment zone (FAZ) and regulates only… Expand
Highly Cited
2009
Highly Cited
2009
Objectives: Polo-like kinase1 (PLK1) belongs to the family of serine/threonine kinases and plays an important role in centrosome… Expand
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2008
2008
Polo-Kinase 1 (PLK1) is a key cell cycle regulator that is necessary for checkpoint recovery after DNA damage-induced G2 arrest… Expand