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GW 3965

Known as: GW-3965, GW3965 
National Institutes of Health

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2 relations

Broader (2)

BenzoatesBenzylamines

Papers overview

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2014
2014
Up-Regulation of the ATP-Binding Cassette Transporter A1 Inhibits Hepatitis C Virus Infection
Hepatitis C virus (HCV) establishes infection using host lipid metabolism pathways that are thus considered potential targets for… 
Highly Cited
2014
Highly Cited
2014
Activation of Liver X Receptor Decreases Atherosclerosis in Ldlr−/− Mice in the Absence of ATP-Binding Cassette Transporters A1 and G1 in Myeloid Cells
Objective—Liver X receptor (LXR) activators decrease atherosclerosis in mice. LXR activators (1) directly upregulate genes… 
2014
2014
Activation of liver X receptor enhances the proliferation and migration of endothelial progenitor cells and promotes vascular repair through PI3K/Akt/eNOS signaling pathway activation.
2014
2014
Liver X Receptor Regulation of Thyrotropin-Releasing Hormone Transcription in Mouse Hypothalamus Is Dependent on Thyroid Status
Reversing the escalating rate of obesity requires increased knowledge of the molecular mechanisms controlling energy balance… 
2013
2013
CARDIOVASCULAR , PULMONARY , AND RENAL PATHOLOGY Lipid Droplet Accumulation Is Associated with an Increase in Hyperglycemia-Induced Renal Damage Prevention by Liver X Receptors
From the Department of Cellular and Molecular Pathology,* German Cancer Research Center, Heidelberg, Germany; the Institute of… 
2012
2012
The LXR agonist GW3965 increases apoA-I protein levels in the central nervous system independent of ABCA1.
2012
2012
LXRβ activation increases intestinal cholesterol absorption, leading to an atherogenic lipoprotein profile
Abstract.  Hu X, Steffensen KR, Jiang Z‐Y, Parini P, Gustafsson J‐Å, Gåfvels M, Eggertsen G (Karolinska Institutet, Huddinge… 
2011
2011
A novel role for c-Jun N-terminal kinase and phosphoinositide 3-kinase in the liver X receptor-mediated induction of macrophage gene expression
2008
2008
Niemann-Pick C1-Like 1 Is Required for an LXR Agonist to Raise Plasma HDL Cholesterol in Mice
Objectives—Activation of liver x receptor (LXR) raises plasma HDL-cholesterol (HDL-C) in mice. Interestingly, the LXR agonist… 
2008
2008
FXRalpha down-regulates LXRalpha signaling at the CETP promoter via a common element.
The cholesteryl ester transfer protein (CETP), a key player in cholesterol metabolism, has been shown to promote the transfer of… 
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