Skip to search formSkip to main contentSkip to account menu

GUCY2F gene

Known as: GUANYLATE CYCLASE 2F, RETINAL, RetGC-2, GUC2DL 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Inferring Novel Tumor Suppressor Genes with a Protein-Protein Interaction Network and Network Diffusion Algorithms
2016
2016
Functional Study and Mapping Sites for Interaction with the Target Enzyme in Retinal Degeneration 3 (RD3) Protein *
Retinal degeneration 3 (RD3) protein, essential for normal expression of retinal membrane guanylyl cyclase (RetGC) in… 
2012
2012
Retinal Guanylyl Cyclase Isozyme 1 Is the Preferential In Vivo Target for Constitutively Active GCAP1 Mutants Causing Congenital Degeneration of Photoreceptors
Two calcium-sensitive guanylyl cyclase activating proteins (GCAP1 and GCAP2) activate cGMP synthesis in photoreceptor by retinal… 
2012
2012
Gucy2f zebrafish knockdown – a model for Gucy2d-related leber congenital amaurosis
Mutations in retinal-specific guanylate cyclase (Gucy2d) are associated with Leber congenital amaurosis-1 (LCA1). Zebrafish offer… 
Review
2009
Review
2009
Novel functions of photoreceptor guanylate cyclases revealed by targeted deletion
Targeted deletion of membrane guanylate cyclases (GCs) has yielded new information concerning their function. Here, we summarize… 
Highly Cited
2008
Highly Cited
2008
A Role for GCAP2 in Regulating the Photoresponse
Cyclic GMP serves as the second messenger in visual transduction, linking photon absorption by rhodopsin to the activity of ion… 
Highly Cited
2006
Highly Cited
2006
Somatic mutations of GUCY2F, EPHA3, and NTRK3 in human cancers
Tyrosine kinases are major regulators of signal transduction cascades involved in cellular proliferation and have important roles… 
Review
1999
Review
1999
Regulation of photoreceptor membrane guanylyl cyclases by guanylyl cyclase activator proteins.
Guanylyl cyclase (GC) plays a central role in the responses of vertebrate rod and cone photoreceptors to light. cGMP is an… 
Highly Cited
1998
Highly Cited
1998
The kinase homology domain of retinal guanylyl cyclases 1 and 2 specifies the affinity and cooperativity of interaction with guanylyl cyclase activating protein-2.
RetGC-1 and RetGC-2 are photoreceptor membrane guanylyl cyclases that are regulated by the Ca2+-binding protein, GCAP-2. We used… 
Highly Cited
1995
Highly Cited
1995
Cloning and expression of a second photoreceptor-specific membrane retina guanylyl cyclase (RetGC), RetGC-2.
One of the membrane guanylyl cyclases (GCs), RetGC, is expressed predominantly in photoreceptors. No extracellular ligand has… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)