GSK962040
National Institutes of Health
Papers overview
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The gut hormone motilin stimulates gastrointestinal motility by inducing gastric phase III of the migrating motor complex (MMC…
BACKGROUND
Camicinal is a novel, nonmacrolide, motilin receptor agonist that accelerates gastric emptying in critically ill…
BackgroundThe promotility agents currently available to treat gastroparesis and feed intolerance in the critically ill are…
Introduction: Gastroparesis is a syndrome of delayed gastric emptying in the absence of mechanical obstruction that presents with…
The gastrointestinal hormone motilin has been known about for >40 years, but after identification of its receptor and subsequent…
withgreat interest and pleasure. The failure of TZP-102 totreat patients with diabetic gastroparesis must notterminate interest…
Background GSK962040, a small molecule motilin receptor agonist, was identified to address the need for a safe, efficacious…
Abstract There is an urgent clinical need for a safe, efficacious stimulant of gastric emptying; current therapies include…
There is an urgent clinical need for a safe, efficacious stimulant of gastric emptying; current therapies include erythromycin…
N-(3-fluorophenyl)-1-[(4-([(3S)-3-methyl-1-piperazinyl]methyl)phenyl)acetyl]-4-piperidinamine 12 (GSK962040) is a novel small…