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GSK 461364A

Known as: GSK-461364A, GSK461364A 
 
National Institutes of Health

Papers overview

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2018
2018
Polo-like kinase 1 (Plk1), a crucial regulator of cell-cycle progression, is overexpressed in multiple types of cancers and has… Expand
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2018
2018
Glioblastoma Multiforme (GBM) is a common primary brain cancer with a poor prognosis and a median survival of less than 14 months… Expand
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2016
2016
Gemcitabine is the standard-of-care for chemotherapy in patients with pancreatic adenocarcinoma and it can directly incorporate… Expand
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2013
2013
Glioblastoma multiforme (GBM) is the most common primary brain tumour in the United States of America (USA) with a median… Expand
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Review
2013
Review
2013
Significant advances in cancer treatment have resulted from the targeted cancer therapy by understanding the process of malignant… Expand
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2013
2013
BACKGROUND Poorly differentiated thyroid carcinoma (PDTC) and anaplastic thyroid carcinoma (ATC) are the most aggressive forms of… Expand
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2011
2011
Few therapeutic strategies exist for the treatment of metastatic tumor cells in the brain because the blood–brain barrier (BBB… Expand
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2010
2010
Polo-like kinases are a family of serine threonine kinases that are critical regulators of cell cycle progression and DNA damage… Expand
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Highly Cited
2009
Highly Cited
2009
Polo-like kinase 1 (Plk1) is a conserved serine/threonine kinase that plays an essential role in regulating the many processes… Expand
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2009
2009
In recent years no cancer therapeutic class has undergone more prolific or successful drug development efforts than the kinase… Expand
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