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National Institutes of Health
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Unexpected finding of delayed-onset seizures in HIV-positive, treatment-experienced subjects in the Phase IIb evaluation of fosdevirine (GSK2248761).
Corpus ID: 6147197
BACKGROUND Fosdevirine (GSK2248761) is a non-nucleoside reverse transcriptase inhibitor with HIV-1 activity against common…
Central nervous system disposition and metabolism of Fosdevirine (GSK2248761), a non-nucleoside reverse transcriptase inhibitor: an LC-MS and Matrix-assisted laser desorption/ionization imaging MS…
M. R. Groseclose
Chemical research in toxicology
Corpus ID: 20249996
The CNS disposition and metabolism of Fosdevirine (FDV), an HIV non-nucleoside reverse transcriptase inhibitor, was investigated…
Drug interaction profile for GSK2248761, a next generation non-nucleoside reverse transcriptase inhibitor.
British journal of clinical pharmacology
Corpus ID: 205255910
AIM To evaluate potential drug interactions with antiretroviral therapies or supportive therapies for use in conjunction with the…
Safety and Efficacy of GSK2248761, a Next-Generation Nonnucleoside Reverse Transcriptase Inhibitor, in Treatment-Naive HIV-1-Infected Subjects
M. S. St Clair
Antimicrobial Agents and Chemotherapy
Corpus ID: 12450271
ABSTRACT GSK2248761 is a novel, once-daily (QD), next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI) with…
IDX-899, an aryl phosphinate-indole non-nucleoside reverse transcriptase inhibitor for the potential treatment of HIV infection.
Olga M. Klibanov
Roberta L Kaczor
Current opinion in investigational drugs
Corpus ID: 24309744
Antiretroviral drug resistance is one of the complications of highly active antiretroviral therapy (HAART). Second-generation non…
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