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GSK 1440115
Known as:
GSK-1440115
, GSK1440115
National Institutes of Health
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2017
2017
A Novel Urotensin II Receptor Antagonist, KR-36996 Inhibits Smooth Muscle Proliferation through ERK/ROS Pathway
Tae-Ho Kim
,
Dong Gil Lee
,
Young-Ae Kim
,
B. Lee
,
K. Yi
,
Yi-Sook Jung
Biomolecules & Therapeutics
2017
Corpus ID: 20190927
Urotensin II (UII) is a mitogenic and hypertrophic agent that can induce the proliferation of vascular cells. UII inhibition has…
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2010
2010
GSK1562590, a slowly dissociating urotensin‐II receptor antagonist, exhibits prolonged pharmacodynamic activity ex vivo
DJ Behm
,
NV Aiyar
,
+12 authors
Sara E Douglas
British Journal of Pharmacology
2010
Corpus ID: 45756518
BACKGROUND AND PURPOSE Recently identified antagonists of the urotensin–II (U‐II) receptor (UT) are of limited utility for…
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