GSAP gene

Known as: gamma-secretase activating protein, PION, GAMMA-SECRETASE-ACTIVATING PROTEIN 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1962-2017
05101519622017

Papers overview

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2015
2015
BACKGROUND A major feature of Alzheimer's disease (AD) is the accumulation of amyloid-beta (Aβ), whose formation is regulated by… (More)
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2014
2014
Accumulation of neurotoxic amyloid-β (Aβ) is a major hallmark of Alzheimer's disease (AD) pathology and an important player in… (More)
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2014
2014
Toxic amyloid-β40-42 (Aβ40-42) peptide cleaved from Aβ protein precursor by β- and γ secretases plays a crucial role in the… (More)
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2013
2013
γ-Secretase is a large enzyme complex comprising presenilin, nicastrin, presenilin enhancer 2, and anterior pharynx-defective 1… (More)
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2012
2012
AIMS A recent study showed that γ-secretase activating protein (GSAP), derived from a C-terminal fragment of pigeon homolog (PION… (More)
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2012
2012
The transmembrane protease complex γ-secretase is responsible for the generation of the neurotoxic amyloid β-peptide (Aβ) from… (More)
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2012
2012
Alzheimer's disease is a fatal neurological disorder that is a leading cause of death, with its prevalence increasing as the… (More)
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2010
2010
The strong-interaction shift πD 1s and broadening Γ πD 1s in pionic deuterium have been determined in a high statistics study of… (More)
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2010
2010
Accumulation of neurotoxic amyloid-β is a major hallmark of Alzheimer’s disease. Formation of amyloid-β is catalysed by… (More)
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1997
1997
  • G. Wanders
  • 1997
Constraints on the parameters in the oneand two-loop pion-pion scattering amplitudes of standard chiral perturbation theory are… (More)
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