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GS-458967

National Institutes of Health

Papers overview

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2016
2016
Mechanisms of Diastolic Dysfunction in Cardiovascular Disease Inhibition of late Na current , a novel target to improve diastolic function and electrical abnormalities in Dahl salt-sensitive rats
Chi L, Belardinelli L, Zeng A, Hirakawa R, Rajamani S, Ling H, Dhalla AK. Inhibition of late Na current, a novel target to… 
2014
2014
Abstract 15303: GS-458967, a Selective Late Sodium Current Inhibitor, Prohibits Torsades de Pointes Arrhythmias in the Chronic Atrioventricular Block Dog Model
Introduction: GS-458967 (GS) is a novel selective and highly potent late sodium current (INaL) inhibitor. Hypothesis: GS was…