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Acyl-CoA:glycerol-sn-3-phosphate acyltransferase (GPAT) is an enzyme responsible for the rate-limiting step in the synthesis of… Expand Glycerol-3-phosphate acyltransferase (GPAT) is the rate-limiting enzyme in the de novo pathway of glycerolipid synthesis. It… Expand Copy number variations (CNVs) are important genetic variants complementary to SNPs, and can be considered as biomarkers for some… Expand This study investigated how maternal overnutrition and obesity regulate expression and activation of proteins that facilitate… Expand We studied the expression pattern and the mechanisms governing the transcription of GPAT2, an enzyme that is highly expressed in… Expand The de novo synthesis of glycerolipids in mammalian cells begins with the acylation of glycerol-3-phosphate, catalyzed by… Expand Glycerol-3-phosphate acyltransferase (GPAT) is a rate-limiting enzyme in mammalian triacylglycerol biosynthesis. GPAT is a target… Expand Elucidation of the metabolic pathways of triacylglycerol (TAG) synthesis is critical to the understanding of chronic metabolic… Expand Glycerol-3-phosphate acyltransferases (GPATs; EC220.127.116.11) catalyze the first step in the de novo synthesis of neutral lipids… Expand Glycerol-3-phosphate acyltransferase (GPAT) catalyzes the initial and rate-limiting step in glycerolipid synthesis. Several… Expand