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GP 1447

Known as: GP-1447 
National Institutes of Health

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2 relations

Broader (2)

PhenylacetatesThiazoles

Papers overview

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2010
2010
Hyperglycemia impairs acetylcholine-induced vasodilation of retinal arterioles through polyol pathway-independent mechanisms in rats.
We previously reported that acetylcholine (ACh)-induced vasodilation of retinal arterioles is diminished in diabetic rats… 
2008
2008
A novel high resolution in vivo digital imaging system for the evaluation of experimental cataract in diabetic rats.
The purpose of this study was to establish a novel imaging system for evaluation of cataract in small animals. Diabetic cataract… 
2000
2000
An enzymatic assay for myo-inositol in tissue samples.
1998
1998
Amelioration of neurovascular deficits in diabetic rats by a novel aldose reductase inhibitor, GP-1447: minor contribution of nitric oxide.
1997
1997
Effects of a novel potent aldose reductase inhibitor, GP-1447, on aldose reductase activity in vitro and on diabetic neuropathy and cataract formation in rats.
GP-1447 {3-[(4,5,7-trifluorobenzothiazol-2-yl) methyl]-5-methylphenylacetic acid}, a novel aldose reductase (AR) inhibitor… 
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