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GO-203

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Abstract 3824: Targeting MUC1-C oncoprotein inhibits AKT-S6K1-elF4A pathway regulated TIGAR translation in colorectal cancer
Colorectal cancer is third most common malignancy and is the second most common cause of cancer-related death. The MUC1 multi… 
2015
2015
LYMPHOID NEOPLASIA Mucin 1 is a potential therapeutic target in cutaneous T-cell lymphoma
PrimarycutaneousT-cell lymphomas(CTCL)compriseaheterogeneous group of non-Hodgkin lymphomas arising from skin tropic T cells. The… 
2014
2014
MUC 1-C confers EMT and KRAS independence in mutant KRAS lung cancer cells
Non-small cell lung cancers (NSCLCs) that harbor an oncogenic KRAS mutation are often associated with resistance to targeted… 
2013
2013
Inhibition of the MUC1-C oncoprotein is synergistic with cytotoxic agents in the treatment of breast cancer cells
Mucin 1 (MUC1) is a heterodimeric glycoprotein that is aberrantly overexpressed in most human breast cancers. The oncogenic MUC1… 
2013
2013
Oncogenic MUC1-C Promotes Tamoxifen Resistance in Human Breast Cancer
Tamoxifen resistance of estrogen receptor-positive (ER+) breast cancer cells has been linked in part to activation of receptor… 
2013
2013
Cell Death and Survival Oncogenic MUC 1-C Promotes Tamoxifen Resistance in Human Breast Cancer
Tamoxifen resistance of estrogen receptor-positive (ERþ) breast cancer cells has been linked in part to activation of receptor… 
2012
2012
Abstract 2243: Targeting the MUC1-C oncoprotein synergistically enhances cytotoxicity of breast carcinoma cells in combination with PI3K inhibitors
Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL The mucin 1 (MUC1) heterodimeric protein is… 
2011
2011
MUC1-C Oncoprotein Blocks Terminal Differentiation of Chronic Myelogenous Leukemia Cells by a ROS-Mediated Mechanism.
Chronic myelogenous leukemia (CML) inevitably progresses to a blast phase by mechanisms that are not well understood. The MUC1-C… 
2011
2011
Therapeutic Discovery Dependence on the MUC 1-C Oncoprotein in Non – Small Cell Lung Cancer Cells
Non–small cell lung cancer (NSCLC) cells are often associated with constitutive activation of the phosphoinositide 3-kinase (PI3K… 
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