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GO 201

Known as: GO-201, GO201 cpd 
 
National Institutes of Health

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1 relation

Broader (1)

Peptides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
MUC1 intracellular bioactivation mediates lung fibrosis
Background Serum KL6/mucin 1 (MUC1) has been identified as a potential biomarker in idiopathic pulmonary fibrosis (IPF), but the… Expand
2018
2018
Inhibition of MUC1-C entering nuclear suppresses MYC expression and attenuates malignant growth in esophageal squamous cell carcinoma
Background The mucin 1 (MUC1) heterodimeric protein (N-terminal subunit and C-terminal subunit) is aberrantly overexpressed in… Expand
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2016
2016
Cigarette Smoke Mediates Nuclear to Cytoplasmic Trafficking of Transcriptional Inhibitor Kaiso through MUC1 and P120-Catenin.
Lung cancer is the leading cause of cancer-related death, and 87% of these deaths are directly attributable to smoking. Using… Expand
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2013
2013
Disrupting BCR-ABL in combination with secondary leukemia-specific pathways in CML cells leads to enhanced apoptosis and decreased proliferation.
Chronic myeloid leukemia (CML) is a myeloproliferative disorder caused by expression of the fusion gene BCR-ABL following a… Expand
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2012
2012
MUC1c Regulates Cell Survival in Pancreatic Cancer by Preventing Lysosomal Permeabilization
Background MUC1 is a type I transmembrane glycoprotein aberrantly overexpressed in various cancer cells including pancreatic… Expand
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Highly Cited
2011
Highly Cited
2011
MUC1-C Oncoprotein Promotes STAT3 Activation in an Autoinductive Regulatory Loop
An inflammatory response of epithelial cells may be co-opted to promote cancer cell survival. Caught in a Loop Mucin 1 (MUC1), a… Expand
2010
2010
Terminal differentiation of chronic myelogenous leukemia cells is induced by targeting of the MUC1-C oncoprotein
Chronic myelogenous leukemia (CML) is caused by expression of the Bcr-Abl fusion protein in hematopoietic stem cells. The MUC1-C… Expand
Highly Cited
2009
Highly Cited
2009
Direct targeting of the mucin 1 oncoprotein blocks survival and tumorigenicity of human breast carcinoma cells.
The mucin 1 (MUC1) oncoprotein is aberrantly overexpressed by approximately 90% of human breast cancers. However, there are no… Expand
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Highly Cited
2009
Highly Cited
2009
MUC1 oncoprotein is a druggable target in human prostate cancer cells
Human prostate cancers are dependent on the androgen receptor for their progression. The MUC1 heterodimeric oncoprotein is… Expand
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2009
2009
MUC 1 oncoprotein is a druggable target in human prostate cancer cells
Human prostate cancers are dependent on the androgen receptor for their progression. The MUC1 heterodimeric oncoprotein is… Expand
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