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GNE-900

National Institutes of Health

Papers overview

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2016
2016
Chk1 kinase is a critical component of the DNA damage response checkpoint and Chk1 inhibitors are currently under clinical… 
2015
2015
Checkpoint kinase 1 (ChK1) plays a key role in the DNA damage response, facilitating cell-cycle arrest to provide sufficient time… 
2013
2013
Checkpoint kinase 1 (ChK1) is a serine/threonine kinase that functions as a central mediator of the intra-S and G2–M cell-cycle… 
2013
2013
Here we report that GNE-783, a novel checkpoint kinase-1 (CHK1) inhibitor, enhances the activity of gemcitabine by disabling the… 
2013
2013
Checkpoint kinase 1 (ChK1) is a serine/threonine kinase that functions as a centralmediator of the intra-S and G2–M cell-cycle… 
2013
2013
Here we report that GNE-783, a novel checkpoint kinase-1 (CHK1) inhibitor, enhances the activity of gemcitabine by disabling the…