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GNE-900

National Institutes of Health

Papers overview

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2013
2013
Small Molecule Therapeutics Identi fi cationof PreferredChemotherapeutics forCombining with a CHK 1 Inhibitor
Here we report that GNE-783, a novel checkpoint kinase-1 (CHK1) inhibitor, enhances the activity of gemcitabine by disabling the… 
2010
2010
492 GNE-900, an orally bioavailable selective CHK1 inhibitor, illustrates that optimal chemosensitization is schedule and tumor type dependent
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