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GLRX wt Allele

Known as: Glutaredoxin1 Gene, Glutaredoxin (Thioltransferase) wt Allele, GRX 
Human GLRX wild-type allele is located in the vicinity of 5q14 and is approximately 72 kb in length. This allele, which encodes glutaredoxin-1… 
National Institutes of Health

Related topics

Related topics

2 relations
HomeostasisOxidation-Reduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Glutaredoxin 1 (GRX1) inhibits oxidative stress and apoptosis of chondrocytes by regulating CREB/HO-1 in osteoarthritis.
2015
2015
Redox regulation of metabolic and signaling pathways by thioredoxin and glutaredoxin in NOS-3 overexpressing hepatoblastoma cells
2011
2011
Segment-specific overexpression of redoxins after renal ischemia and reperfusion: protective roles of glutaredoxin 2, peroxiredoxin 3, and peroxiredoxin 6.
Highly Cited
2010
Highly Cited
2010
Glutaredoxin regulates apoptosis in cardiomyocytes via NFkappaB targets Bcl-2 and Bcl-xL: implications for cardiac aging.
Cardiomyocyte apoptosis is a well-established contributor to irreversible injury following myocardial infarction (MI). Increased… 
Highly Cited
2009
Highly Cited
2009
Glutaredoxin Regulates Autocrine and Paracrine Proinflammatory Responses in Retinal Glial (Müller) Cells*
Protein S-glutathionylation is a reversible redox-dependent post-translational modification. Many cellular functions and signal… 
Highly Cited
2007
Highly Cited
2007
Modulation of glutaredoxin-1 expression in a mouse model of allergic airway disease.
Glutaredoxins (GRX) are antioxidant enzymes that preferentially catalyze the reduction of protein-glutathione mixed disulfides… 
2007
2007
Suppression of Endogenous Antioxidant Enzymes by 2,3,7,8-Tetrachlorodibenzo-p-dioxin–Induced Oxidative Stress in Chicken Liver During Development
Domestic chickens (Gallus gallus) are an excellent model in which to evaluate developmental toxicity and oxidative stress because… 
Highly Cited
2006
Highly Cited
2006
Modulation of glutaredoxin in the lung and sputum of cigarette smokers and chronic obstructive pulmonary disease
BackgroundOne typical feature in chronic obstructive pulmonary disease (COPD) is the disturbance of the oxidant/antioxidant… 
Highly Cited
2004
Highly Cited
2004
Expression of glutaredoxin is highly cell specific in human lung and is decreased by transforming growth factor-beta in vitro and in interstitial lung diseases in vivo.
Highly Cited
1994
Highly Cited
1994
Two additional glutaredoxins exist in Escherichia coli: glutaredoxin 3 is a hydrogen donor for ribonucleotide reductase in a thioredoxin/glutaredoxin 1 double mutant.
Thioredoxin (Trx) and glutaredoxin (Grx1) are hydrogen donors for ribonucleotide reductase, the key enzyme for… 
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