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GL-ONC1
Known as:
GLV-1h68
National Institutes of Health
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Light-Emitting Oncolytic Vaccinia Virus GL-ONC1
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Effective oncolytic vaccinia therapy for human sarcomas.
Shuangba He
,
Pingdong Li
,
+8 authors
R. Wong
The Journal of surgical research
2012
Corpus ID: 45335418
2012
2012
Preferential Replication of Systemically Delivered Oncolytic Vaccinia Virus in Focally Irradiated Glioma Xenografts
S. Advani
,
Lisa Buckel
,
+7 authors
A. Szalay
Clinical Cancer Research
2012
Corpus ID: 5689645
Purpose: Radiotherapy is part of the standard of care in high-grade gliomas but its outcomes remain poor. Integrating oncolytic…
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2011
2011
Insertion of the human sodium iodide symporter to facilitate deep tissue imaging does not alter oncolytic or replication capability of a novel vaccinia virus
D. Haddad
,
N. Chen
,
+11 authors
A. Szalay
Journal of Translational Medicine
2011
Corpus ID: 18394404
IntroductionOncolytic viruses show promise for treating cancer. However, to assess therapeutic efficacy and potential toxicity, a…
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Highly Cited
2009
Highly Cited
2009
Anti-VEGF single-chain antibody GLAF-1 encoded by oncolytic vaccinia virus significantly enhances antitumor therapy
A. Frentzen
,
Y. A. Yu
,
+4 authors
A. Szalay
Proceedings of the National Academy of Sciences
2009
Corpus ID: 205243740
We previously reported that the replication-competent vaccinia virus (VACV) GLV-1h68 shows remarkable oncolytic activity and…
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Highly Cited
2009
Highly Cited
2009
Regression of human pancreatic tumor xenografts in mice after a single systemic injection of recombinant vaccinia virus GLV-1h68
Yong A. Yu
,
C. Galanis
,
+4 authors
A. Szalay
Molecular Cancer Therapeutics
2009
Corpus ID: 23446590
Oncolytic virotherapy of tumors has shown promising results in both preclinical and clinical studies. Here, we investigated the…
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2009
2009
A Novel Recombinant Vaccinia Virus Expressing the Human Norepinephrine Transporter Retains Oncolytic Potential and Facilitates Deep-Tissue Imaging
N. Chen
,
Qian Zhang
,
+8 authors
A. Szalay
Molecular medicine
2009
Corpus ID: 5984028
Noninvasive and repetitive monitoring of a virus in target tissues and/or specific organs of the body is highly desirable for the…
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2009
2009
Use of an oncolytic vaccinia virus for the treatment of canine breast cancer in nude mice: preclinical development of a therapeutic agent
I. Gentschev
,
J. Stritzker
,
+7 authors
A. Szalay
Cancer Gene Therapy
2009
Corpus ID: 25654697
Mammary cancers together with cancers of the skin account for about 60% of the total cancers occurring in dogs. The veterinary…
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Highly Cited
2009
Highly Cited
2009
The highly attenuated oncolytic recombinant vaccinia virus GLV-1h68: comparative genomic features and the contribution of F14.5L inactivation
Qian Zhang
,
Chunguang Liang
,
Yong A. Yu
,
N. Chen
,
T. Dandekar
,
A. Szalay
Molecular Genetics and Genomics
2009
Corpus ID: 2984615
As a new anticancer treatment option, vaccinia virus (VACV) has shown remarkable antitumor activities (oncolysis) in preclinical…
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Highly Cited
2008
Highly Cited
2008
Novel oncolytic agent GLV-1h68 is effective against malignant pleural mesothelioma.
K. Kelly
,
Y. Woo
,
+8 authors
Y. Fong
Human gene therapy
2008
Corpus ID: 5318337
Malignant pleural mesothelioma (MPM) is a fatal disease with a median survival of less than 14 months. For the first time, a…
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Highly Cited
2007
Highly Cited
2007
Eradication of solid human breast tumors in nude mice with an intravenously injected light-emitting oncolytic vaccinia virus.
Qian Zhang
,
Yong A. Yu
,
+5 authors
A. Szalay
Cancer research
2007
Corpus ID: 13433486
Previously, we reported that a recombinant vaccinia virus (VACV) carrying a light-emitting fusion gene enters, replicates in, and…
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