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GKT 136901
Known as:
GKT-136901
, GKT136901
Topic mentions per year
Topic mentions per year
2010-2017
0
1
2
2010
2017
Papers overview
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2018
2018
Effect of NADPH oxidase 1 and 4 blockade in activated human retinal endothelial cells.
Binoy Appukuttan
,
Yuefang Ma
,
+4 authors
Justine R Smith
Clinical & experimental ophthalmology
2018
BACKGROUND Over-production of reactive oxygen species (ROS) and resulting oxidative stress contribute to retinal damage in…
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2017
2017
NOX4 is an early initiator of neuropathic pain.
Christian Geis
,
Eva Geuss
,
Claudia Sommer
,
Harald H H W Schmidt
,
C. Kleinschnitz
Experimental neurology
2017
Treatment of neuropathic pain remains challenging as the etiology is heterogeneous and pathomechanisms are incompletely…
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Review
2016
Review
2016
NADPH Oxidase 4 at the Nexus of Diabetes, Reactive Oxygen Species, and Renal Metabolism.
Eugene Rhee
Journal of the American Society of Nephrology…
2016
NADPH oxidases (NOXs) catalyze the transfer of electrons fromNADPH tomolecular oxygen to produce superoxide and/ or hydrogen…
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2015
2015
NOX4 in Mitochondria: Yeast Two-Hybrid-Based Interaction with Complex I Without Relevance for Basal Reactive Oxygen Species?
Christine Hirschhäuser
,
Julia Bornbaum
,
+8 authors
Harald H H W Schmidt
Antioxidants & redox signaling
2015
NADPH oxidases (NOXs) represent the only known dedicated source of reactive oxygen species (ROS) and thus a prime therapeutic…
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2015
2015
IL-1beta mediates MMP secretion and IL-1beta neosynthesis via upregulation of p22(phox) and NOX4 activity in human articular chondrocytes.
Franccois Rousset
,
Florence Hazane-Puch
,
+7 authors
Bernard Lardy
Osteoarthritis and cartilage
2015
OBJECTIVES Osteoarthritis (OA) is characterized by a progressive alteration of the biochemical properties of the articular…
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2014
2014
The NOX1/4 inhibitor GKT136901 as selective and direct scavenger of peroxynitrite.
Stephanie Schildknecht
,
A. Weber
,
+7 authors
Marcel Leist
Current medicinal chemistry
2014
NADPH oxidases (NOX), catalyzing the reduction of molecular oxygen to form the superoxide radical anion (•O₂⁻) and hydrogen…
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2013
2013
Renoprotective effects of a novel Nox1/4 inhibitor in a mouse model of Type 2 diabetes.
Mona H. Sedeek
,
A. A. Gutsol
,
+11 authors
Rhian M Touyz
Clinical science
2013
Nox (NADPH oxidase)-derived ROS (reactive oxygen species) have been implicated in the development of diabetic nephropathy. Of the…
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2011
2011
Differential regulation of Nox1, Nox2 and Nox4 in vascular smooth muscle cells from WKY and SHR.
Ana María Briones
,
Fatiha Tabet
,
+6 authors
Rhian M Touyz
Journal of the American Society of Hypertension…
2011
The functional significance and regulation of NAD(P)H oxidase (Nox) isoforms by angiotensin II (Ang II) and endothelin-1 (ET-1…
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2010
2010
NADPH oxidases regulate CD44 and hyaluronic acid expression in thrombin-treated vascular smooth muscle cells and in atherosclerosis.
Aleksandr E. Vendrov
,
Nageswara R. Madamanchi
,
+5 authors
Marschall S. Runge
The Journal of biological chemistry
2010
The intracellular signaling events by which NADPH oxidase-generated reactive oxygen species (ROS) modulate vascular smooth muscle…
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2010
2010
NADPH oxidases regulate CD44 and hyaluronic acid expression
Aleksandr E. Vendrov
,
Nageswara R. Madamanchi
,
+4 authors
Patrick Pagé
2010
3 The abbreviations used are: ROS, reactive oxygen species; VSMC, vascular smooth muscle cells, HA, hyaluronic acid; DMEM…
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