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GKLF protein

Known as: epithelial zinc finger protein, gut-enriched Kruppel-like factor, endothelial Kruppel-like zinc finger protein 
Krueppel-like factor 4 (470 aa, ~50 kDa) is encoded by the human KLF4 gene. This protein regulates transcription.
National Institutes of Health

Related topics

Related topics

11 relations
CYS2-HIS2 Zinc FingersCell Differentiation processDNA-Binding ProteinsGenes, Regulator

Broader (2)

Growth InhibitorsKruppel-Like Transcription Factors

Narrower (1)

Klf4 protein, mouse

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Abstract 1833: KLF4 regulates metabolic homeostasis in response to energy stress
Kruppel-like factor 4 (KLF4) is a zinc finger-containing transcription factor with diverse regulatory functions in cellular… 
2018
2018
miR‑3120‑5p acts as a diagnostic biomarker in non‑small cell lung cancer and promotes cancer cell proliferation and invasion by targeting KLF4.
Accumulating evidence indicates that microRNAs (miRs) are important regulators in a number of types of human cancer, including… 
Review
2017
Review
2017
High expression of Kruppel-like factor 4 as a predictor of poor prognosis for cervical cancer patient response to radiotherapy
Purpose: The aim of this study was to explore the associations of Kruppel-like factor 4 expression with sensitivity to radiation… 
2016
2016
A Novel Selectable Islet 1 Positive Progenitor Cell Reprogrammed to Expandable and Functional Smooth Muscle Cells
Disorders affecting smooth muscle structure/function may require technologies that can generate large scale, differentiated and… 
Review
2016
Review
2016
DNA Damage and Epigenetic Changes in Kidney Diseases - Focused on Transcription Factors in Podocytes.
Recently it has been shown that epigenetic mechanisms are involved in initiation and progression of caridiovascular and metabolic… 
2015
2015
Kruppel-Like Factor 4 Regulates Granule Cell Pax6 Expression and Cell Proliferation in Early Cerebellar Development
Kruppel-like factor 4 (Klf4) is a transcription factor that regulates many important cellular processes in stem cell biology… 
2014
2014
Synergistic anti-tumor effect of KLF4 and curcumin in human gastric carcinoma cell line.
Kruppel-like factor 4 is a transcription factor which plays an important role in development and progression of various… 
2013
2013
The transcription factor Krueppel-like factor 4 is a positive regulator of angiogenic properties in endothelial cells
2010
2010
t g of ROR Differentiation of Th17 Cells Independently Kruppel-Like Factor 4 Regulates the Cutting Edge: The Transcription Factor
Th17 cells play a significant role in inflammatory and autoimmune responses. Although a number of molecular pathways that… 
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