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GITR Agonist MEDI1873

Known as: MEDI1873, TNFRSF18 Protein Stimulant MEDI1873, MEDI 1873 
An agonist of human glucocorticoid-induced tumor necrosis factor receptor (tumor necrosis factor superfamily, member 18; TNFRSF18; GITR), with… 
National Institutes of Health

Papers overview

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2018
2018
A phase I study of MEDI1873, a novel GITR agonist, in advanced solid tumors.
2018
2018
GITR cosignal in ILC2s controls allergic lung inflammation.
2016
2016
Abstract 561: MEDI1873: A novel hexameric GITRL fusion protein with potent agonsitic and immunomodulatory activities in preclinical systems
Glucocorticoid-induced TNFR-related protein (GITR) is a member of the tumor necrosis factor receptor (TNFR) superfamily. GITR is… 
2016
2016
A Phase 1 study of MEDI1873 in adult patients with select advanced solid tumors.
TPS3099Background: Directly activating T cells by delivering activating signals that augment those received via the T-cell… 
2015
2015
pGITRL Aktarılan Mezenkimal Kök Hücrelerin Küçük Hücreli Akciğer Kanserine in Vitro Etkisi ve Altın Nanopartiküllerle İşaretlenmesi
Glukokortikoidle induklenen tumor nekrozis faktor reseptoru (GITR) ve ligandi GITRL, tumor nekrozis faktor (TNF) ailesi… 
2014
2014
Protéines de liaison à l'antigène gitr
L'invention concerne des proteines de liaison a l'antigene qui activent GITR. Des acides nucleiques codant pour ces proteines de… 
Review
2014
Review
2014
Cell-specific and context-dependent effects of GITR in cancer, autoimmunity, and infection.
2010
2010
A role for SIK2-TORC1 cascade in neuronal survival after ischemia
2010
2010
GITR (glucocorticoid-induced TNF receptor)-positive T lymphocytes regulate endogenous neurogenesis in post-stroke brain
2008
2008
In vivo expansion of CD4+Foxp3+ regulatory T cells mediated by GITR molecules.
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