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GI 147211

Known as: GI-147211, GI147211 
National Institutes of Health

Related topics

Related topics

2 relations
OSI 211

Broader (1)

lurtotecan

Papers overview

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Review
2005
Review
2005
Randomized trial of two intravenous schedules of the topoisomerase I inhibitor liposomal lurtotecan in women with relapsed epithelial ovarian cancer: a trial of the national cancer institute of…
PURPOSE Liposomal lurtotecan (OSI-211) is a liposomal formulation of the water-soluble topoisomerase I inhibitor lurtotecan… 
2000
2000
Liposomal lurtotecan (NX211): determination of total drug levels in human plasma and urine by reversed-phase high-performance liquid chromatography.
1998
1998
Phase I and pharmacokinetic study of GI147211, a water-soluble camptothecin analogue, administered for five consecutive days every three weeks.
GI1147211 is a 7-substituted 10,11-ethylenedioxy-20(S)-camptothecin analogue that inhibits the nuclear enzyme topoisomerase I. In… 
Review
1997
Review
1997
Topoisomerase I inhibitors: the relevance of prolonged exposure for present clinical development.
Topoisomerase I inhibitors constitute a new class of anti-cancer agents. Recently, topotecan and irinotecan were registered for… 
1997
1997
The bioavailability of oral GI147211 (GG211), a new topoisomerase I inhibitor.
Topoisomerase I inhibitors are new compounds of interest for cancer chemotherapy. We performed a study with GI147211, a new… 
1997
1997
Phase II studies with GI147211 (GI) in breast (B), colorectal (C) and non small cell lung cancer (N)
1996
1996
Phase I and pharmacological study of the new topoisomerase I inhibitor GI147211, using a daily x 5 intravenous administration.
Topoisomerase I inhibitors are interesting anti-cancer agents with a novel mechanism of action. We performed a phase I study with… 
1996
1996
Identification and characterization of the sulfate precipitate in GI147211C IV formulation.
GI147211, a water soluble analog of camptothecin, is currently being investigated for the treatment of cancer as a topoisomerase… 
1995
1995
High-performance liquid chromatographic analysis of the lactone and carboxylate forms of a topoisomerase I inhibitor (the antitumor drug GI147211) in plasma.
1995
1995
Determination of GI147211 in human blood by HPLC with fluorescence detection.
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