GI 147211

Known as: GI-147211, GI147211 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2017
02419952017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2000
2000
BACKGROUND GI147211 is a water-soluble synthetic analogue of camptothecin showing promising in vivo and in vitro antitumor… (More)
Is this relevant?
2000
2000
Lurtotecan (GI147211; LRT) is a semisynthetic and water-soluble analogue of the topoisomerase I inhibitor camptothecin. To… (More)
Is this relevant?
1998
1998
Purpose: We have previously reported that DX-8951f, a water-soluble and nonprodrug camptothecin (CPT) derivative, exhibits both… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
1998
1998
GI1147211 is a 7-substituted 10,11-ethylenedioxy-20(S)-camptothecin analogue that inhibits the nuclear enzyme topoisomerase I. In… (More)
Is this relevant?
1997
1997
The well documented hydrolysis of the alpha-hydroxy-delta-lactone ring moiety in camptothecin and related analogues is routinely… (More)
Is this relevant?
1997
1997
Topoisomerase I inhibitors are a new class of anticancer agents with a mechanism of action aimed at interrupting DNA replication… (More)
Is this relevant?
1997
1997
Topoisomerase I inhibitors are new compounds of interest for cancer chemotherapy. We performed a study with GI147211, a new… (More)
  • table 1
  • table 2
  • table 3
  • table 4
Is this relevant?
1996
1996
Topoisomerase I inhibitors are interesting anti-cancer agents with a novel mechanism of action. We performed a phase I study with… (More)
  • table I
  • table III
  • figure 2
  • figure 1
  • table IV
Is this relevant?
1996
1996
GI147211, a water soluble analog of camptothecin, is currently being investigated for the treatment of cancer as a topoisomerase… (More)
Is this relevant?
1995
1995
The development of camptothecin-like compounds as inhibitors of topoisomerase I for the treatment of resistant tumors has… (More)
Is this relevant?