GGCX, GLY537TYR
National Institutes of Health
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Warfarin is a widely used anticoagulant with a narrow therapeutic index. Polymorphisms in the VKORC1, CYP2C9 and CYP4F2 genes…
Objective Little is known about genetic contributors to higher than usual warfarin dose requirements, particularly for African…
Summary Via generation of vitamin K-dependent proteins, gamma-glutamyl carboxylase (GGCX) plays a critical role in the vitamin K…