Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 236,506,778 papers from all fields of science
Search
Sign In
Create Free Account
GEM231
Known as:
GEM 231
, GEM-231
, Gene Expression Modulator 231
A mixed backbone oligonucleotide exhibiting antitumor activity. GEM-231 is complementary to the RI alpha subunit of Protein Kinase A (PKA), resulting…
Expand
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
1 relation
Broader (1)
Oligonucleotides
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
A phase I trial of an anti-pka oligonucleotide (GEM231) administered with weekly CPT-11
A. Lockhart
,
C. Rudin
,
+7 authors
M. Rothenberg
2004
Corpus ID: 201139049
2074 Background: PKA RIa is a primary mediator of cAMP activity and is upregulated in many cancers. GEM231 (G) is a 2nd…
Expand