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GE2270A

 
National Institutes of Health

Papers overview

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2017
2017
Significance Synthetic [4+2] cycloaddition reactions are prevalent and useful transformations employed in syntheses of valuable… Expand
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Review
2010
Review
2010
Antibiotics of the thiocillin, GE2270A, and thiostrepton class, which block steps in bacterial protein synthesis, contain a… Expand
2008
2008
The total syntheses of the thiopeptide antibiotics GE2270A (7), GE2270T (8), and GE2270C1 (9) are described. The original… Expand
Highly Cited
2006
Review
2002
Review
2002
Since the pioneering discovery of the inhibitory effects of kirromycin on bacterial elongation factor Tu (EF-Tu) more than 25… Expand
2000
2000
The antibiotic GE2270A prevents stable complex formation between elongation factor Tu (EF-Tu) and aminoacyl-tRNA (aatRNA). In… Expand
2000
2000
The structure of a 1:1 molar complex between Escherichia coli elongation factor (EF) Tu-GDP and the cyclic thiazolyl peptide… Expand
Highly Cited
1999
Highly Cited
1999
Elongation factor Tu (EF-Tu) is encoded by the tuf gene of the plastid organelle of the malaria parasite Plasmodium falciparum. A… Expand
1997
1997
Sensitivity of EF-Tu1 of the GE2270A producer Planobispora rosea towards GE2270A, pulvomycin and kirromycin was determined by… Expand
1997
1997
MDL 62,879 (GE2270A) 1 is a new inhibitor of elongation factor-Tu (EF-Tu) and belongs to the class of thiazolyl peptide… Expand
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