GCHFR gene

Known as: GTP cyclohydrolase I feedback regulator, GCHFR, GFRP 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1975-2016
0102019752016

Papers overview

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2010
2010
RATIONALE GTP cyclohydrolase I (GTPCH-1) is the rate-limiting enzyme involved in de novo biosynthesis of tetrahydrobiopterin (BH… (More)
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2005
2005
Alterations in tetrahydrobiopterin (BH4) levels have significant consequences in vascular pathophysiology. However, the… (More)
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2004
2004
GTP cyclohydrolase I (GTPCHI) is the rate-limiting enzyme involved in the biosynthesis of tetrahydrobiopterin, a key cofactor… (More)
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2004
2004
Over the last two decades fiber-reinforced polymer (FRP) rods have emerged as one of the most promising and affordable solutions… (More)
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2002
2002
In the presence of phenylalanine, GTP cyclohydrolase I feedback regulatory protein (GFRP) forms a stimulatory 360-kDa complex… (More)
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2001
2001
GTP cyclohydrolase I feedback regulatory protein (GFRP) mediates the feedback inhibition of GTP cyclohydrolase I activity by (6R… (More)
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1999
1999
Tetrahydrobiopterin, the coenzyme required for hydroxylation of phenylalanine, tyrosine, and tryptophan, regulates its own… (More)
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1998
1998
The activity of GTP cyclohydrolase I is inhibited by (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin (BH4) and stimulated by… (More)
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1998
1998
2,4-Diamino-6-hydroxypyrimidine (DAHP) is considered to be a selective and direct-acting inhibitor of GTP cyclohydrolase I (GTPCH… (More)
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1997
1997
GTP cyclohydrolase I feedback regulatory protein (GFRP) mediates feedback inhibition of GTP cyclohydrolase I activity by… (More)
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